Can vitamin B12 cause heart problems?

Yes, Vitamin B12 significantly affects heart health, primarily by helping lower homocysteine, an amino acid linked to increased heart disease risk, though studies show B12 supplements don't necessarily reduce overall cardiovascular risk, but deficiency can be a problem, especially for vegetarians. B12 deficiency can raise homocysteine levels, damaging arteries, but supplementing doesn't always prevent heart attacks or strokes despite lowering homocysteine, suggesting other factors are involved.


What are the negatives to taking B12?

While Vitamin B12 is generally safe, excessive intake, especially via injections, can cause side effects like headaches, diarrhea, nausea, dizziness, and tingling; rarely, severe reactions include anaphylaxis or heart issues, and very high blood levels (often from illness, not supplements) have been linked to increased mortality or certain cancers. For most, high doses from supplements are considered safe as the body excretes excess, but it's important to monitor for adverse effects and consult a doctor, especially with pre-existing conditions.
 

Does vitamin B12 interact with amlodipine?

No specific major interactions are listed for Vitamin B12 and amlodipine (a blood pressure medication), meaning they are generally considered safe to take together, but it's always best to check with your doctor or pharmacist before combining supplements like B vitamins with prescription drugs like amlodipine to ensure there are no individual concerns or potential interactions with other supplements. 


Can vitamin B12 cause headaches?

Taking doses of vitamin B-12 might cause: Headache. Nausea.

Why does vitamin B12 make my heart race?

Heart Palpitations and Chest Tightness After Taking Vitamin B12 Concerns include anxiety-induced palpitations and digestive upset with supplements. Vitamin B12 at typical doses rarely causes heart palpitations or chest tightness. These symptoms may be related to anxiety or other underlying conditions.


Can Vitamin B12 Deficiency Cause Heart Palpitations? - Cardiology Community



How do you feel if your B12 is too high?

Too much vitamin B12 usually causes mild symptoms like headaches, nausea, diarrhea, weakness, or tingling in hands/feet, but serious issues are rare and often linked to injections or underlying conditions, with signs like severe anxiety, heart palpitations, difficulty breathing, or acne, requiring a doctor's visit as high levels can sometimes signal other health problems.
 

Is B12 good for heart rate?

Frank vitamin B12 deficiency associated with pernicious anemia is characterized by lowered heart rate variability of both sympathetic and parasympathetic components (Sözen et al., 1998) and these changes are reversed with vitamin B12 supplementation (Aytemir et al., 2000).

Can vitamin B12 cause blood clots?

Vitamin B12 is involved in the breakdown of a protein called homocysteine. High homocysteine levels are associated with an increased risk of heart disease and stroke as it may promote the formation of blood clots and excess free radical cells, and may impair normal blood vessel function.


What kind of B12 is best for seniors?

Active B12 is generally considered to be the best form of B12 for seniors for several reasons. Metabolically active forms of B12 such as methylcobalamin and adenocobalamin require no further conversion in the body.

Why do I feel worse after B12?

Feeling worse after a B12 shot often reflects an initial “healing crisis” as your body repairs cells and releases stored toxins. You can ease symptoms by staying well-hydrated, resting, and working with your doctor to adjust your dose or injection schedule.

Is it okay to take B12 if you have high blood pressure?

The 2025 U.S. guideline on hypertension does not list a warning about routine B vitamin use with blood pressure medication. However, while it is appropriate to supplement additional Vitamin B if you have a deficiency, there are no formal recommendations on Vitamin B supplementation for high blood pressure.


What not to mix with amlodipine?

Cautions with other medicines

Some medicines can affect the way amlodipine works. Tell your doctor if you're taking any of these medicines before starting amlodipine: antibiotics such as clarithromycin, erythromycin or rifampicin. calcium channel blockers like diltiazem or verapamil.

What medications should you not take B12 with?

You should be cautious taking Vitamin B12 with medications that reduce stomach acid (like omeprazole, famotidine) or are for diabetes (metformin) as they can hinder B12 absorption, and also with certain gout drugs (colchicine) and antibiotics (chloramphenicol). High doses of Vitamin C might also interfere with absorption, so space them out. Always check with a doctor, as these interactions usually affect absorption rather than causing direct harm. 

Who should avoid taking B12?

They need to know if you have any of these conditions:
  • Anemia.
  • Kidney disease.
  • Leber's disease.
  • Malabsorption disorder.
  • An unusual or allergic reaction to cyanocobalamin, cobalt, other medications, foods, dyes, or preservatives.
  • Pregnant or trying to get pregnant.
  • Breast-feeding.


What organ does vitamin B12 affect?

Vitamin B12 does a lot of important things for your body. It helps create your DNA and red blood cells, for example. Your body also needs B12 for the development of your central nervous system (your brain and spinal cord).

What is the problem with vitamin B12?

Vitamin B12 deficiency can also cause symptoms that affect your brain and nervous system (neurological symptoms), including: numbness. muscle weakness. psychological problems, which can range from mild depression or anxiety, to confusion and dementia.

Should people over 70 take B12?

If you are an older adult, you should be taking a supplement for B12 as well as trying to incorporate B12 into your diet. It is vital for good health and cognitive functioning. Studies continue to show all the ways it is beneficial for your overall health.


Is B12 a risk factor for strokes?

A vitamin B12 deficiency can increase homocysteine levels, which are a well-established risk factor for ischemic stroke.

What two vitamins should not be taken together?

For vitamins and minerals, these should not be taken together:
  • Calcium and magnesium.
  • Calcium and iron.
  • Zinc and copper.
  • Calcium and iron.


What is the number one cause of blood clots?

The most common causes of blood clots stem from issues slowing blood flow (immobility, surgery), damage to blood vessels (injury, disease), or inherited/acquired clotting disorders, with prolonged inactivity (like long travel or bed rest), recent surgery, heart conditions (like atrial fibrillation), cancer, and certain medications significantly increasing risk, but often it's a combination of these factors. 


Can I take B12 with heart problems?

Vitamin B12 protects against cardiovascular disease including heart attack and stroke. It does this by lowering the levels of an amino acid in the blood called homocysteine. High homocysteine levels are associated with the development of heart disease.

What are the facial signs of B12 deficiency?

Cutaneous manifestations associated with vitamin B12 deficiency are skin hyperpigmentation, vitiligo, angular stomatitis, and hair changes. A diagnosis of vitamin B12 deficiency is often overlooked in its early stages because these signs are not specific to vitamin B12 deficiency alone.

Which vitamin is not good for heart patients?

Excess levels of vitamin B3 linked with increased heart disease risk. New research suggests that high levels of niacin, also known as vitamin B3, may increase cardiovascular disease risk.