Does lupus cause dementia?

A new study has found a significant association between dementia and the most common form of lupus, and that patients with the autoimmune disease are at high risk for early vascular dementia (VaD) and should be screened to prevent occurrence.


Can lupus cause memory problems?

People with lupus can have cognitive symptoms, like having a hard time thinking clearly or remembering things. This is also called “brain fog” or “lupus fog,” and it often comes and goes over time. In some people, lupus fog can be present for many years.

How do you know if lupus is affecting your brain?

Symptoms include: Confusion and trouble concentrating (sometimes called lupus brain fog) Seizures (sudden, unusual movements or behavior) Stroke (blocked blood flow in the brain that causes brain cells to die)


Does lupus cause alzheimers?

Cognitive dysfunction occurs in many people with lupus, but it is usually not severe. Likewise, lupus fog usually does not progress to the level of dementia or Alzheimer's disease.

Why does lupus cause memory loss?

Researchers from The Feinstein Institute for Medical Research have discovered that the activation of brain cells called microglia likely contributes to the memory loss and other cognitive impairments suffered by many patients with systemic lupus erythematosus (SLE).


Lupus - Signs & Symptoms



What is the life expectancy with lupus?

The prognosis of lupus is better today than ever before. With close follow-up and treatment, 80-90% of people with lupus can expect to live a normal life span.

What are three triggers of lupus?

Common triggers include:

Overwork and not enough rest. Being out in the sun or having close exposure to fluorescent or halogen light. Infection. Injury.

What autoimmune diseases cause dementia?

Among the patients with ARDs, the subgroups with rheumatoid arthritis, systemic lupus erythematosus, and Sjögren syndrome (SS) were associated with a significantly higher dementia risk (adjusted hazard ratio [HR] 1.14, 95% confidence index [CI] 1.06–1.32; adjusted HR 1.07, 95% CI 0.86–1.34; adjusted HR 1.46, 95% CI ...


What is the most common organ affected by lupus?

Certain cells and processes of the immune system have been identified as playing a role in lupus. Kidneys About one half of people with lupus experience kidney involvement, and the kidney has become the most extensively studied organ affected by lupus.

Are you born with lupus or can you get it later in life?

Most infants of mothers with lupus are healthy. It is also possible for an infant to have neonatal lupus even though the mother does not have lupus currently. But, if a baby is born with lupus, often the mother will develop lupus later in life.

Can lupus cause dementia like symptoms?

A growing body of evidence indicates that systemic lupus erythematosus (SLE) is associated with increased risk of cognitive impairment and dementia.


Can you see lupus on brain MRI?

Magnetic resonance imaging (MRI) is the gold standard technique for studying the brain in lupus (Sarbu et al., 2015c). The neuroimaging findings are classified as small or large vessel disease, and inflammatory-type lesions (Sarbu et al., 2015b).

What are the most severe symptoms of lupus?

Lupus symptoms include: 1,2
  • Muscle and joint pain. You may experience pain and stiffness, with or without swelling. ...
  • Fever. A fever higher than 100 degrees Fahrenheit affects many people with lupus. ...
  • Rashes. ...
  • Chest pain. ...
  • Hair loss. ...
  • Sun or light sensitivity. ...
  • Kidney problems. ...
  • Mouth sores.


What is lupus hair?

But some people with lupus develop round (discoid) lesions on the scalp. Because these discoid lesions scar your hair follicles, they do cause permanent hair loss. Lupus can also cause the scalp hair along your hairline to become fragile and break off easily, leaving you with a ragged appearance known as lupus hair.


Does lupus cause mental issues?

Lupus and its treatments can impair mental & emotional health. 80-90% of people with lupus. Neuropsychiatric lupus describes feelings of depression, headaches, and lupus fog — trouble thinking or remembering due to lupus. 25% of lupus patients experience major depression and 37% have major anxiety, research shows.

Why does lupus cause confusion?

The exact cause of lupus fog is hard to pin down, experts say. In some cases, lupus can damage cells in the brain, leading directly to cognitive problems. However, in most cases other factors play a role, including fatigue, stress, and depression. Lupus fog is sometimes worse in people who also have fibromyalgia.

What is the most serious complication of lupus?

Lupus can cause serious kidney damage, and kidney failure is one of the leading causes of death among people with lupus. Brain and central nervous system. If your brain is affected by lupus, you may experience headaches, dizziness, behavior changes, vision problems, and even strokes or seizures.


What jobs to avoid with lupus?

Many lupus patients aren't able to do intensive physical work, like waitressing or working in a grocery store. Jobs that involve standing for long periods, like working a cash register, greeting customers, or being a hostess at a restaurant, can be physically tiring as well as rough on the joints.

What is the number one symptom of lupus?

The most common lupus symptoms (which are the same for men and women) are: Extreme fatigue (feeling tired all the time) Pain or swelling in the joints. Swelling in the hands, feet, or around the eyes.

What are the top 3 diseases that cause dementia?

Causes
  • Alzheimer's disease. This is the most common cause of dementia. ...
  • Vascular dementia. This type of dementia is caused by damage to the vessels that supply blood to your brain. ...
  • Lewy body dementia. ...
  • Frontotemporal dementia. ...
  • Mixed dementia.


What are the two main diseases that cause dementia?

Alzheimer's disease. This is the most common cause of dementia. Vascular dementia. This may occur in people who have long-term high blood pressure, severe hardening of the arteries, or several small strokes.

What disease most commonly causes dementia?

Alzheimer's disease is the most common type of dementia. Alzheimer's disease is thought to be caused by the abnormal build-up of 2 proteins called amyloid and tau. Deposits of amyloid, called plaques, build up around brain cells.

What is the most common cause of death in lupus?

Until recently, the most common cause of death in people with lupus was kidney failure. Now, with better therapies, access to dialysis, and the possibility of kidney transplantation, the frequency of death from kidney disease has decreased sharply. However, kidney failure is still fatal in some people with lupus.


What are the four stages of lupus?

The four different types of lupus
  • Systemic lupus erythematosus (SLE) Systemic lupus is the most common form of lupus—it's what most people mean when they refer to “lupus.” Systemic lupus can be mild or severe.
  • Cutaneous lupus erythematosus. ...
  • Drug-induced lupus erythematosus. ...
  • Neonatal lupus.


What vitamins should I avoid with lupus?

People with lupus should avoid certain supplements, including echinacea, spirulina, and vitamin E. These supplements may increase the immune system response and trigger lupus symptoms. It is also helpful to avoid excess sun exposure, salt, and alfalfa sprouts, which may also make symptoms worse.