How many months can you take terbinafine?

For some infections, such as fungal nail infections, you may need to take terbinafine tablets for up to 3 months (sometimes longer). It is safe to take long-term if your doctor tells you to.

How many rounds of terbinafine can you take?

The standard dose for a terbinafine pulse regimen is 500 mg per day for 7 days a month, twice or three times for fingernails and three to four times for toenails [28].

How long does it take for terbinafine to damage liver?

Clinically apparent liver injury from terbinafine occurs rarely (1 in 50,000 to 120,000 prescriptions), but many case reports and even case series have been described in the literature. Liver injury usually arises within the first 6 weeks of therapy.

Does terbinafine keep working after you stop taking it?

Since fungal infections may be very slow to clear up, you may need to take this medicine for several weeks or months. If you stop taking this medicine too soon, your symptoms may return. This medicine works best when there is a constant amount in the blood.

How long does it take terbinafine to clear toenail fungus?

Systemic medications recommended for treating severe widespread skin infection or nails infected with one of fungal organisms: Terbinafine: 250mg tablets daily (or 125mg twice daily) for 6 weeks for fingernails, 3 to 6 months for toenails.

Treating Toenail Fungus with Lamisil

Can you take terbinafine for more than 3 months?

For some infections, such as fungal nail infections, you may need to take terbinafine tablets for up to 3 months (sometimes longer). It is safe to take long-term if your doctor tells you to.

Does toenail fungus come back after terbinafine?

A 7-year prospective study of 73 onychomycosis patients who were successfully treated (mycological and clinical cure) with continuous terbinafine or intermittent itraconazole showed that recurrence occurred at a mean time of 36 months after successful treatment [8].

How long should you be on terbinafine?

You will usually take the tablets for anywhere from 6 weeks to 3 months. But, if you have a nail infection of the big toe or your nails grow very slowly, you may need to take the tablets for up to 6 months. It may take several months after you stop taking Lamisil tablets for your nail to look completely normal.

Are there long term effects of terbinafine?

Although most side effects are mild and self-limited, such as headache and gastrointestinal symptoms, taste disturbances (dysgeusia) can range from mild to severe, resulting in weight loss, and have rarely been reported permanent.

Does terbinafine cause permanent liver damage?

It's true that liver injury is a potential side effect of terbinafine. But liver failure does not commonly occur. In fact, liver injury from terbinafine use only occurs in an estimated 1 in 50,000 to 120,000 prescriptions . If liver injury does occur, it usually happens within the first 6 weeks of taking terbinafine.

How do I know if terbinafine is affecting my liver?

Any symptoms of persistent nausea, anorexia, fatigue, vomiting, right upper abdominal pain or jaundice, dark urine, or pale stools must be reported. Patients with these symptoms should discontinue taking the drug, and the patient's liver function should be immediately evaluated.

Is it worth taking terbinafine?

Terbinafine has an average rating of 6.3 out of 10 from a total of 456 ratings on Drugs.com. 55% of reviewers reported a positive experience, while 33% reported a negative experience.

How common is liver damage with antifungals?

In a large meta-analysis of antifungals tolerability and hepatotoxicity, the risk of liver injury with standard dose of fluconazole not requiring treatment discontinuation was 9.3%, while the risk of drug discontinuation due to elevated liver enzymes was 0.7% [74].

What is the success rate of terbinafine?

Forty-eight percent achieved a clinical cure compared with only 6% of the placebo group (RR 6.00, 95% CI 3.96 to 9.08; 8 studies, 1,006 people). The mycological cure rate was 59% vs 17% with placebo (RR 4.53, 95% CI 2.47 to 8.33) though there was high variability between individual studies for this outcome.

What can I take instead of terbinafine?

Does terbinafine get rid of toenail fungus?

Terbinafine belongs to the group of medicines called antifungals. It is used to treat fungus infections of the scalp, body, groin (jock itch), feet (athlete's foot), fingernails, and toenails. This medicine is available only with your doctor's prescription.

Is terbinafine hard on kidneys?

The clinical history combined with the diagnostic findings suggest acute kidney injury and rhabdomyolysis associated with terbinafine use.

What happens if you drink coffee while taking terbinafine?

You may need to limit your Caffeine intake while receiving Terbinafine tablets. Too much Caffeine can cause effects like nausea, nervousness, or sleeplessness. Terbinafine skin creams do not interact. Notes for Professionals: Terbinafine has been shown to inhibit the clearance of caffeine.

Does terbinafine make your hair fall out?

Extract. Sir, Terbinafine is an allylamine antifungal agent which is widely used in the treatment of dermatophytes, achieving a mycological cure in more than 80% of patients. We report a case of hair loss following treatment with terbinafine for onychomycosis.

Is terbinafine hard on the liver?

Terbinafine is a common antifungal drug used for onychomycosis that may cause hepatotoxicity with an incidence of 0.5–3/100,000 exposed. Terbinafine cause several types of hepatotoxicity that include acute hepatitis, cholestasis or mixed picture, acute liver failure and vanishing bile duct syndrome.

Is liver damage from terbinafine reversible?

Terbinafine-induced liver injury has been reported in the literature. 2-5 The majority of the cases are reversible after discontinuation of the drug. There is at least one report of acute liver failure due to this drug.

Why is terbinafine hard on your liver?

Like many drugs, terbinafine is metabolised by the liver and excreted by the kidneys, consequently a reduction in function of either of those two organ systems could result in serious problems if prescribed to the wrong patient.

What is the number one cure for toenail fungus?

Terbinafine for toenail fungus treatment

The best pill for toenail fungus is terbinafine. Evidence suggests it works better than the alternatives with the fewest side effects. Terbinafine results in resolution of toenail fungus 76% of the time.

How do you know when toe fungus is gone?

Toenails usually grow less than 2mm per month and the infection has to grow out completely before you can consider a fungal toenail “cured.”

What happens if you have toenail fungus for too long?

A severe case of nail fungus can be painful and may cause permanent damage to your nails. And it may lead to other serious infections that spread beyond your feet if you have a suppressed immune system due to medication, diabetes or other conditions.