Is 10000 mcg B12 daily too much?

Supplementation of 25-100 mcg per day has been used to maintain vitamin B12 levels in older people. For vitamin B12 deficiency: Vitamin B12 doses of 300-10,000 mcg daily have been used. However, some evidence suggests that the most effective oral dose is between 647-1032 mcg daily.

Is 10,000 units of B12 too much?

Is taking high doses of B12 helpful or harmful? Since B12 is a water-soluble vitamin, it's generally considered safe, even at high doses. No Tolerable Upper Intake Level (UL) has been established for B12, due to its low level of toxicity.

What is the maximum amount of B12 I can take in a day?

There is no upper limit for vitamin B12, and most supplements provide between 500 mcg to 5,000 mcg of B12 daily to meet various nutritional needs [2].

Can you overdose on vitamin B12?

When taken at appropriate doses, vitamin B-12 supplements are generally considered safe. While the recommended daily amount of vitamin B-12 for adults is 2.4 micrograms, higher doses have been found to be safe. Your body absorbs only as much as it needs, and any excess passes through your urine.

Can you take more than 1000 mcg of B12 a day?

There is no risk of an overdose when taking large amounts of vitamin B-12 such as 1000 mcg, because it is a water-soluble vitamin. Meaning the body will use the amount that it needs then the excess will be excreted through urine.

The Optimal Vitamin B12 Dosage for Adults

What is considered high B12?

An elevated B12 is generally defined as a level higher than the upper limit of the normal range, around 1000 ± 100 ng/L (738 ± 73.8 pmol/L)^2,3,4.

Can B12 cause neuropathy?

B12 deficiency may cause demyelination of nerves in the peripheral and central nervous system¹³ and has been associated with peripheral neuropathy, loss of sensation in peripheral nerves, and weakness in lower extremities in older adults^{1, 14–16}.

What are the symptoms of overdosing on vitamin B12?

How much B12 should a woman take daily?

Most women get the recommended daily amount — 2.4 micrograms (mcg) for most adults, 2.6 mcg for pregnant women, and 2.8 mcg for women who are breastfeeding — in their diets.

How long does vitamin B12 last in your system?

Stores of vitamin B12 in the body can last around 2 to 4 years without being replenished, so it can take a long time for any problems to develop after a dietary change.

Does B12 affect your eyes?

Disturbed or blurred vision can also occur as a result of a Vitamin B12 deficiency. This happens when the deficiency causes damage to the optic nerve that leads to your eyes. The nervous signal that travels from the eye to the brain is disturbed due to this damage, leading to impaired vision.

What medications should not be taken with B12?

As summarized in the table provided, vitamin B12 (cobalamin) absorption and utilization by the body can be compromised with the chronic use of certain medications which include: colchicine, chloramphenicol, ethanol, histamine 2 receptor antagonists (H2RA), metformin, and proton pump inhibitors (PPI).

What strength B12 should I take?

The usual dose for: diet-related deficiency is 50 micrograms to 150 micrograms, taken once a day. B12 deficiency not caused by your diet is one to two 1,000 microgram tablets, taken once or twice a day – this is usually if you cannot have vitamin B12 injections.

How long does it take for B12 to work?

Once you begin treating your vitamin B12 deficiency, it can take up to six to 12 months to fully recover. It is also common to not experience any improvement during the first few months of treatment.

How does excess B12 leave the body?

Vitamin B12 is a water-soluble vitamin. Water-soluble vitamins dissolve in water. After the body uses these vitamins, leftover amounts leave the body through the urine.

Can too much B12 make you feel weird?

In rare cases, people who take high doses of vitamin B for a long period of time may experience extreme numbness or a tingling sensation. In some patients, tingling sensation is experienced mostly in the right side of the body. This symptom is one of the early warning indicators of Vitamin B12 overdose.

Can B12 raise blood pressure?

Discussion. We found that a higher intake of vitamin B12 was associated with lower systolic and diastolic blood pressure and a higher intake of folic acid was associated with lower systolic blood pressure in children.

Can B12 affect your feet?

Vitamin B₁₂deficiency symptoms may include: strange sensations, numbness, or tingling in the hands, legs, or feet. difficulty walking (staggering, balance problems)

How can I test my B12 levels at home?

What does B12 neuropathy feel like?

pins and needles (paraesthesia) loss of physical co-ordination (ataxia), which can affect your whole body and cause difficulty speaking or walking. damage to parts of the nervous system (peripheral neuropathy), particularly in the legs.

Is 5000 mcg of B12 too much?

Is 5000 mcg of B12 too much? A dosage of 5000 mcg of Vitamin B12 has been deemed a safe dosing amount. In fact, it is often recommended for those who have a health condition that affects their B12 absorption.

Does B12 affect kidney function?

Vitamin B12 deficiency in the background of CKD and ESKD leads to insufficient renal transsulfuration of homocysteine, contributing to increased plasma homocysteine levels.

When should I take B12 morning or night?

Vitamin B12

As a general rule of thumb, take your B vitamins in the morning or with a meal. Vitamin B12, for example, should definitely be taken in the morning. This is because it is important for energy metabolism, which may interrupt your sleep if taken at night.

How many mg of B12 should a senior take?

Recommended Vitamin B12 Dosage for Seniors

A recent study found that for seniors, a daily dose of 500 micrograms was efficient in reversing the signs of B12 deficiency. In general, experts recommend 2.5 micrograms of vitamin B12 per day for people over the age of 14.

What stops vitamin B12 being absorbed?

[1] People who regularly take medications that suppress stomach acid for conditions like gastroesophageal reflux disease (GERD) or peptic ulcer disease—such as proton-pump inhibitors, H2 blockers, or other antacids—may have difficulty absorbing vitamin B12 from food.