Is levothyroxine hard on the heart?

This is especially true in patients with heart failure. While levothyroxine replacement may improve heart failure, it is possible that in this group it could have harmful effects, especially if the levothyroxine dose is too high.


Can long term use of levothyroxine cause heart problems?

The studies proving this are not limited in numbers, they demonstrate an association between long-term levothyroxine therapy and increased risk of heart disease, osteoporosis, and fractures.

What are the dangers of levothyroxine?

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  • Chest pain, discomfort, or tightness.
  • decreased urine output.
  • difficult or labored breathing.
  • difficulty with swallowing.
  • dilated neck veins.
  • extreme fatigue.
  • fast, slow, irregular, pounding, or racing heartbeat or pulse.
  • heat intolerance.


What does levothyroxine do to heart rate?

Treatment with levothyroxine in those with overt thyroid dysfunction has been shown to improve LDL cholesterol, total cholesterol, triglycerides, hypertension, diastolic dysfunction, heart rate, and heart rate variability in exercise and to delay progression of atherosclerosis.

Can thyroid medicine hurt your heart?

Signs your thyroid medicine is too high can include tremors, shakiness, feeling nervous, jittery or anxious, cardiac palpitations - a fluttering in the chest. See your doctor if you have those symptoms as your medicine may need to be reduced.


How is Thyroid Linked to Heart Disease?



Is there a downside to taking thyroid medication?

Side Effects of Thyroid Medication

Increased sweating. Mood swings/Irritability. Nervousness. Fatigue.

Can heart patients take levothyroxine?

If cardiac disease, consider treatment if TSH is persistently 0.1–0.4 mIU/L. With known coronary artery disease, start low-dose levothyroxine and increase dose slowly. If unable to tolerate full dose, additional measures to treat CVD are indicated.

Can levothyroxine cause congestive heart failure?

Among patients with heart failure, levothyroxine therapy may increase risk for all-cause death, major adverse cardiovascular events and CV death, independent of whether the patient is treated before or after the heart failure diagnosis, according to an analysis of Danish registry data.


Does levothyroxine impact blood pressure?

In 15 patients with hypertension and hypothyroidism, levothyroxine therapy showed only a small decrease in blood pressure (151/105 +/- 9/9 mm Hg, group A). The remaining 15 patients showed complete normalization of blood pressure (118/83 +/- 8/3 mm Hg, group B).

Is 125 mcg of levothyroxine a lot?

While body weight may influence the dose to some degree, the average replacement dose of levothyroxine to return the TSH back to normal is in the 100–125 mcg range.

Why should you not stop taking levothyroxine?

Stopping levothyroxine usually leads to the return of hypothyroidism symptoms. In the review mentioned above, only about 12% of people with overt hypothyroidism were able to stop their thyroid medications successfully. If you've had your thyroid completely removed, you'll need thyroid medications for life.


What should I avoid while taking levothyroxine?

In addition, absorption of levothyroxine may be decreased by foods such as soybean flour, cotton seed meal, walnuts, dietary fiber, calcium, and calcium fortified juices. These foods should be avoided within several hours of dosing if possible.

Is Synthroid better than levothyroxine?

As previously mentioned, one version isn't technically better than the other. Both generic levothyroxine and Synthroid should work equally well for the treatment of hypothyroidism. It's just not ideal to switch back and forth between different products, unless you're directed to do so.

What is the alternative to taking levothyroxine?

Levothyroxine doesn't work for everyone. Armour Thyroid, Cytomel, Thyrolar, Synthroid, and Levoxyl are some levothyroxine alternatives.


Is there a natural replacement for levothyroxine?

Desiccated thyroid is a natural preparation, and it was the only treatment for hypothyroidism before levothyroxine was available. It has a characteristic, strong odor. Armour Thyroid is the most common desiccated thyroid.

What is the most significant adverse effect of thyroid drugs?

The most dangerous effect is agranulocytosis, which occurs in 0.1 to 0.5% of patients. This life-threatening condition can now be effectively treated by granulocyte colony-stimulating factor administration.

Can levothyroxine cause blood clots?

Using levothyroxine can cause changes to your levels of thyroid hormone that could make these problems worse. For people with blood clotting disorders: Let your doctor know if you have any blood clotting disorders. Taking levothyroxine may make it more difficult for your blood to clot and make bleeding more likely.


Why is it better to take levothyroxine at night?

In conclusion, bedtime intake of levothyroxine in our study significantly improved thyroid hormone levels. This may be explained by better gastrointestinal bioavailability at night or by less uptake interference by food or medications. As shown in this study, bedtime administration is more convenient for many patients.

Can levothyroxine give you heart palpitations?

Taking Synthroid may cause heart-related side effects, such as heart palpitations or an increased heart rate. If you're an older adult, you may be at a higher risk for these side effects.

What organ systems are affected by levothyroxine?

The Effects of Hypothyroidism on the Body
  • Endocrine system. When you have hypothyroidism, your body makes too little of the thyroid hormones T3 and T4. ...
  • Circulatory and cardiovascular systems. ...
  • Nervous system. ...
  • Respiratory system. ...
  • Digestive system. ...
  • Reproductive system. ...
  • Other systems.


Can levothyroxine cause atrial fibrillation?

Older adults taking levothyroxine at higher doses may be at an increased risk of developing atrial fibrillation (AF) compared to patients taking lower doses, according to the findings of a population-based observational study.

When should you stop taking thyroid medication?

To obtain a high level of TSH, your doctor may choose to temporarily stop your thyroid hormone medication four to six weeks before treatment with radioactive iodine (RAI), or for diagnostic testing. This process is called thyroid hormone withdrawal (THW). Normal levels of TSH are between 0.4 to 4 mlU/L.

What happens if you don't take thyroid medication for hypothyroidism?

Untreated hypothyroidism can lead to serious complications, including heart disease and nerve damage. In rare cases, it can be fatal. Most people with hypothyroidism have to take thyroid hormone replacement long term. You will need ongoing thyroid level checks to ensure you are on the right dose.


Does levothyroxine cause anxiety?

Levothyroxine is a common treatment for hypothyroidism, but if your dose is too high, it can directly lead to anxiety and cause symptoms like rapid heartbeat and shakiness, which can make anxiety worse, says Rosenfeld.

What is the best prescription thyroid medication?

The most common treatment is levothyroxine (Levoxyl, Synthroid, Tirosint, Unithroid, Unithroid Direct), a man-made version of the thyroid hormone thyroxine (T4). It acts just like the hormone your thyroid gland normally makes.