What are the negative effects of vitamin D3?

Is there a downside to taking vitamin D3?

Some side effects of taking too much vitamin D include weakness, dry mouth, nausea, vomiting, and others. Taking vitamin D for long periods of time in doses higher than 4000 IU (100 mcg) daily is possibly unsafe and may cause very high levels of calcium in the blood.

What organs does vitamin D3 affect?

Vitamin D undergoes further chemical changes, first in the liver and then in the kidneys, to become calcitriol. Calcitriol acts on the intestine, kidneys, and bones to maintain normal levels of blood calcium and phosphorus.

What are the side effects of taking vitamin D3?

Serious side effects of Vitamin D3

Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.

Who should not take vitamin D3 supplements?

Vitamin D Toxicity Rare in People Who Take Supplements, Mayo Clinic Researchers Report

What medications Cannot be taken with vitamin D3?

Phenobarbital, phenytoin, and other anticonvulsant medications -- These medications may accelerate the body's use of vitamin D. Mineral oil -- Mineral oil also interferes with absorption. In addition, Vitamin D may enhance the effects of doxorubicin , a medicine used to treat a variety of cancers.

Is it good to take vitamin D3 everyday?

In very high doses, many minerals (like iron) and vitamins can harm your body. Current guidelines say adults shouldn't take more than the equivalent of 100 micrograms a day. But vitamin D is a 'fat-soluble' vitamin, so your body can store it for months and you don't need it every day.

How does vitamin D3 make you feel?

2. Vitamin D may regulate mood and reduce depression. Research has shown that vitamin D might play an important role in regulating mood and decreasing the risk of depression. A review of 7,534 people found that those experiencing negative emotions who received vitamin D supplements noticed an improvement in symptoms.

Is vitamin D3 hard on your kidneys?

"The public should know that taking more vitamin D than is recommended does not necessarily lead to added benefit. Rather, it can lead to increased harm and specifically kidney failure," he added.

Does vitamin D3 affect any medications?

Growing scientific evidence suggests that vitamin D₃–drug interactions may impact specific patient groups and increase their risk of low vitamin D status, particularly those prescribed medications like statins and corticosteroids.

What are signs of low vitamin D?

How much vitamin D3 should a woman take daily?

A: The upper tolerable limit is 4,000 international units (IU) daily, and the recommended amount for women 14 to 70 is 600 IU per day. Women 71 and older should aim for 800 IU per day.

Does D3 cause kidney stones?

The largest meta-analysis by Malihi et al. concluded that vitamin D2 and D3 supplementation resulted in changes in calcium metabolism, with increased risks of hypercalcemia and hypercalciuria, but no increase in the risk of reported kidney stones [14].

Does vitamin D3 affect potassium levels?

Vitamin D3 tended to increase retention of both potassium and sodium in the body. A significant interaction occurred between dietary magnesium and vitamin D3 relative to body weight gain. Vitamin D3 increased magnesium content in tibiae ash and decreased magnesium content in serum.

What happens when you start taking vitamin D3?

Vitamin D3 is more efficient than D2. You get vitamin D from food, supplements, and sunshine. Vitamin D is important for bone and muscle strength and immune function. It may help prevent depression, inflammatory disease, and heart disorders.

Does vitamin D3 give you energy?

Vitamin D keeps your immune system strong and can help regulate insulin levels. It keeps your energy levels up and enhances your mood, too.

How long should you take vitamin D3?

If your blood levels are exceptionally low, you may need higher doses that should be used under the direction of a healthcare provider. In patients with vitamin D levels less than 20 ng/mL, start with 50,000 IUs of vitamin D3 once a week for 6 to 8 weeks.

Should vitamin D3 be taken morning or night?

We recommend taking it with a source of quality fat in the morning or when you break your fast. Avoid taking vitamin D in the evening (we'll talk about why below). Since vitamin D is a fat-soluble vitamin—meaning it doesn't dissolve in water—your body can most easily absorb it when you take it with food.

Is it better to take vitamin D3 every day or once a week?

Oral vitamin D3 can be taken once a day but also with longer intervals because of its long half life, being around 25 days. It is not known whether equivalent doses once a week or once a month are equally effective.

Can too much D3 be harmful?

Vitamin D is important for your bones, muscles, nerves, immune system, and more. But if you get too much, it could lead to a rare and possibly serious condition called vitamin D toxicity. You may hear your doctor call it hypervitaminosis D. The condition can bring symptoms like weakness and vomiting.

Does caffeine interfere with d3 absorption?

Research also demonstrated that the higher the level of caffeine, the more it interfered with vitamin D absorption. The study suggested that caffeine did this by reducing the expression of vitamin D receptors on osteoblasts in the body – the cells responsible for producing bone.

What blocks absorption of vitamin d3?

Does d3 damage liver?

Hepatotoxicity. Neither normal nor excessively high intakes of vitamin D are associated with liver injury or liver test abnormalities.

What vitamins are hard on kidneys?

You may need to avoid some vitamins and minerals if you have kidney disease. Some of these include vitamins A, E and K. These vitamins are more likely to build up in your body and can cause harm if you have too much.

Can d3 cause heart palpitations?

Taking too much vitamin D is not good either, as it can lead to hypercalcemia, or high calcium levels, which can also cause irregular heartbeat.