What are the two most common adverse effects of statins?

Side effects can vary between different statins, but common side effects include: headache. dizziness.


What is the most serious acute side effect of statin therapy?

Very rarely, statins can cause life-threatening muscle damage called rhabdomyolysis (rab-doe-my-OL-ih-sis). Rhabdomyolysis can cause severe muscle pain, liver damage, kidney failure and death. The risk of very serious side effects is extremely low, and calculated in a few cases per million people taking statins.

Which statin has the most side effects?

Looking at the most commonly used statins – both brand names and, when available, generic forms of the drugs – rosuvastatin, the strongest statin, had the highest rates of reported problems. This was followed by atorvastatin, simvastatin, pravastatin, and lovastatin.


What are the two downsides of taking statins?

The most common side effects of statins include nausea, vomiting, and aches and pains in the muscles and joints. You may also have constipation, gas, or diarrhea. Most people are able to take statins without experiencing side effects, and the most common side effects of statins are mild.

What is the most serious side effect of atorvastatin?

Serious side effects

you get unexplained muscle pain, tenderness, weakness or cramps – these can be signs of muscle breakdown and kidney damage.


Statin Side Effects Lesson 2 (Psychological, Behavioral, & Neurological Side Effects)



What is the best statin with the least side effects?

According to a research review people who take simvastatin (Zocor) or pravastatin (Pravachol) may experience fewer side effects.

What is the downside of atorvastatin?

Worsening liver problems and liver failure

Though rare, atorvastatin (Lipitor) can cause serious liver problems that can lead to liver failure. You'll need to get blood tests to check your liver health before and during treatment to make sure their liver is working properly.

What can I take instead of statins to lower cholesterol?

7 cholesterol-lowering alternatives to statins
  • Fibrates. Mostly used for lowering triglyceride levels in patients whose levels are very high and could cause pancreatitis. ...
  • Plant stanols and sterols. ...
  • Cholestyramine and other bile acid-binding resins. ...
  • Niacin. ...
  • Policosanol. ...
  • Red yeast rice extract (RYRE) ...
  • Natural products.


Can you stop taking statins once you start?

If you're taking a statin medication to lower your cholesterol, you will need to keep taking your prescription, or your cholesterol will likely go back up. Stopping your statin can put you at risk of having heart disease and other preventable health problems like stroke and heart attack from high cholesterol.

Is it better not to take statins?

If your risk is very low, you probably won't need a statin, unless your LDL is above 190 mg/dL (4.92 mmol/L). If your risk is very high — for example, you've had a heart attack in the past — a statin may be helpful even if you don't have high cholesterol.

What is the best statin that doesn't cause muscle pain?

Even though all statins are similar chemically, they have some minor differences that could impact how likely they are to cause muscle pain. Simvastatin is the most likely to cause muscle pain, and fluvastatin is the least likely.


What is the first drug of choice for cholesterol?

Statins are the most common medicine for high cholesterol. They reduce the amount of cholesterol your body makes. You take a tablet once a day. You usually need to take them for life.

What is the best statin drug on the market?

Rosuvastatin and atorvastatin are the best at lowering LDL cholesterol.

Why would a patient not want to take statins?

Fear of side effects and perceived side effects are the most common reasons for declining or discontinuing statin therapy. Willingness to take a statin is high, among both patients who have declined statin therapy and those who have never been offered one.


What patients should statin drugs be avoided?

People at an increased risk of side effects
  • being over 70 years old.
  • having a history of liver disease.
  • regularly drinking large quantities of alcohol.
  • having a history of muscle-related side effects when taking a statin or fibrate (another type of medicine for high cholesterol)


Which statin has least liver side effects?

Adverse Effects and Hepatotoxicity

Simvastatin, lovastatin, fluvastatin, and atorvastatin are metabolized by cytochrome P-450, while pravastatin, rosuvastatin, and pitavastatin remain almost unaffected by any hepatic metabolic processes.

Can you take a statin just once a week?

Discussion. Our analysis of current evidence suggests that intermittent statin administration is effective in lowering LDL levels in patients with dyslipidemia. All dosing regimens, including alternate days, 3 to 5 times a week, 2 to 3 times a week, and once a week, were shown to be effective.


What should a 70 year old cholesterol be?

After having their cholesterol tested, seniors should be given a number between 190 and 260. Healthy seniors should keep their total cholesterol below 200 and their LDL cholesterol around 100. If your elderly loved one's LDL cholesterol level is above 160, he or she must start making sweeping lifestyle changes.

Can you skip a day of statins?

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Do not take 2 doses of this medicine if it has been more than 12 hours since you missed your last dose.

What is the best prescription to lower cholesterol?

Statins — Statins are one of the best-studied classes of medications and the most commonly used drugs for lowering LDL cholesterol. They are the most effective drugs for prevention of coronary heart disease, heart attack, stroke, and death.


What is a natural substitute for statin drugs?

These natural alternatives to statins include: Exercise.
...
Natural Alternatives to Statins: Foods That Help Lower Cholesterol
  • Foods high in soluble fiber and plant phytosterols, such as legumes, avocados, broccoli and other fruits and vegetables.
  • Whole grains, including oatmeal, quinoa and barley.


What reduces cholesterol quickly naturally?

Oatmeal, oat bran and high-fiber foods

Soluble fiber is also found in such foods as kidney beans, Brussels sprouts, apples and pears. Soluble fiber can reduce the absorption of cholesterol into your bloodstream. Five to 10 grams or more of soluble fiber a day decreases your LDL cholesterol.

Why would a doctor stop atorvastatin?

Dr. Carimi says muscle-related complications are the most common side effect from taking statins. “The most common reason people stop taking statins is because of side effects, like muscle aches, but many have muscle pains from other causes and stop taking the medication in error,” Dr. Carimi says.


What damage can atorvastatin cause?

summarized several forms of side effects attributed to the use of atorvastatin, including hepatocellular injury, cholestatic injury, mixed pattern of atorvastatin-associated hepatocellular and cholestatic injury, autoimmune-type reaction and fulminant liver failure [2].

How do I get off statins?

Reducing statin use
  1. Adding other cholesterol drugs. Drugs your doctor could add to your medication regimen while reducing your statin use include ezetimibe, bile acid sequestrants, or niacin. ...
  2. Adding L-carnitine supplements.
  3. Adding CoQ10 supplements.