What bacteria does metronidazole target?

Metronidazole has activity against protozoans like Entamoeba histolytica, Giardia lamblia and Trichomonas vaginalis, for which the drug was first approved as an effective treatment. Anaerobic bacteria which are typically sensitive are primarily Gram-negative anaerobes belonging to the Bacteroides and Fusobacterium spp.

What type of bacteria does metronidazole treat?

Metronidazole is one of the mainstay drugs for the treatment of anaerobic bacterial infections, protozoal infections, and microaerophilic bacterial infections.

Does metronidazole treat gram-positive or Gram-negative bacteria?

Metronidazole is an important drug for the management of infections caused by anaerobic organisms (including Gram-negative bacteria, Gram-positive bacteria, and protozoa).

Is metronidazole a broad spectrum antibiotic?

Outline dosing of metronidazole for some of the more common indications. Describe the importance of antibiotic stewardship when initiating a broad-spectrum antimicrobial like metronidazole.

Does metronidazole destroy good bacteria?

While metronidazole is effective in getting rid of the bad bacteria that causes an infection, it may also destroy helpful bacteria that normally live in the vagina. This can lead to a disruption in the environment of the vagina and an overgrowth of yeast.

Metronidazole | Bacterial Targets, Mechanism of Action, Adverse Effects

Does metronidazole treat all infections?

Metronidazole is an antibiotic that is used to treat a wide variety of infections. It works by stopping the growth of certain bacteria and parasites. This antibiotic treats only certain bacterial and parasitic infections. It will not work for viral infections (such as common cold, flu).

Does metronidazole treat E coli?

The viable numbers of all strains of E. coli tested were considerably reduced by metronidazole, even at sub-MIC levels, and the effect was greater when DNA repair lesions were more severe.

Can metronidazole treat Staphylococcus aureus?

Furthermore, an additional reduction in the number of S. aureus was noted in mixed infections with bacteroides that were treated with metronidazole alone. The antimicrobial synergy in vitro and in vivo between metronidazole and spiramycin may have clinical implications that deserve to be further investigated.

Does metronidazole treat aerobic bacteria?

Metronidazole is an effective agent for the treatment of anaerobic infections. Because metronidazole is not active against facultative and aerobic bacteria, the addition of a second antimicrobial agent may be required for the treatment of mixed anaerobic-aerobic infections.

Is metronidazole a first-line antibiotic?

Metronidazole is first-line treatment for mild to moderate C. difficile infection. A 10 – 14 day course is recommended because, although 70% of patients respond to metronidazole in five days, 91% respond with a 14 day course. Metronidazole can be given by intravenous infusion if oral treatment is inappropriate.

Will metronidazole treat chlamydia?

Official answer. Metronidazole does not treat chlamydia and is not a recommended treatment for chlamydia, but it may be given if symptoms of chlamydia persist after finishing a course of first-line treatments for chlamydia such as doxycycline, azithromycin, or levofloxacin.

Does metronidazole always cure BV?

BV is treated with antibiotics, of which oral and vaginal formulations of metronidazole or clindamycin are most commonly used. Although short-term BV cure rates of multiday oral and vaginal metronidazole regimens are 65%–90%,^{11, 12} recurrence rates are high. Metronidazole is a nitroimidazole-class drug.

Does metronidazole treat streptococcus?

WASHINGTON — Metronidazole is effective in the treatment of non-β-hemolytic streptococcal tonsillitis, Itzhak Brook, M.D., reported in a poster presentation at the annual Interscience Conference on Antimicrobial Agents and Chemotherapy.

Is BV aerobic or anaerobic?

BV is typically polymicrobial, characterized by the presence of mainly anaerobic microorganisms including Gardnerella vaginalis, Prevotella species, and Mycoplasma hominis, Mobiluncus species (8, 24, 25).

Does metronidazole cover MRSA?

Interestingly, a series of 35 metronidazole-triazole hybrids on screening against MRSA were found to be active. Compound 22 was found to be effective at 4 μg/mL concentration against nine strains of MRSA.

What is the strongest antibiotic for staph infection?

For serious staph infections, vancomycin may be required. This is because so many strains of staph bacteria have become resistant to other traditional antibiotics.

Is metronidazole antibacterial or antifungal?

Metronidazole belongs to the class of medicines known as antibiotics. It works by killing the bacteria or preventing their growth. However, this medicine will not work for vaginal fungus or yeast infections. This medicine is available only with your doctor's prescription.

What antibiotic kills staphylococcus?

Rifampin and ciprofloxacin have been shown to be the most effective intraphagocytic killing agents, while clindamycin and erythromycin were inactive in these in vitro assays.

What should you not take with metronidazole?

What antibiotic kills E. coli the best?

In rare cases, antibiotics are used for certain traveler's diarrhea and infant diarrhea only in cases of fever or persistent diarrhea. Fluoroquinolones, such asciprofloxacin, andlevofloxacin, are usually the first-line therapy. Azithromycin is also commonly used as treatment for invasive E. coli infections.

How long does it take for metronidazole to work for bacterial infection?

Metronidazole starts to work 1 to 2 hours after you take it, because it is quickly absorbed, and it reaches its maximum concentration after 20 minutes to 3 hours. But it may take a couple of days before you start to feel better or notice an improvement in your symptoms.

Can metronidazole treat UTI and BV?

Description and Brand Names

Metronidazole is used to treat bacterial infections in different areas of the body. The extended-release tablets are used to treat women with vaginal infections (bacterial vaginosis). Metronidazole belongs to the class of medicines known as antibiotics.

Is metronidazole better than amoxicillin?

Amoxicillin has an average rating of 6.3 out of 10 from a total of 350 ratings on Drugs.com. 52% of reviewers reported a positive effect, while 32% reported a negative effect. Metronidazole has an average rating of 6.1 out of 10 from a total of 2369 ratings on Drugs.com.

How quickly does metronidazole work?

For most infections, you should feel better within a few days. With serious swelling, including dental infections, the medicine will start working within a few days but it may take longer before your symptoms start to get better.

What STD does doxycycline and metronidazole treat?

Sixteen women received ciprofloxacin, and 20 received doxycycline plus metronidazole. Both regimes eradicated Chlamydia trachomatis in all cases and Neisseria gonorrhoeae in all except one in which combination treatment failed because of resistance of the organism to tetracycline.