What does years of depression do to your brain?

There's growing evidence that several parts of the brain shrink in people with depression. Specifically, these areas lose gray matter volume (GMV). That's tissue with a lot of brain cells. GMV loss seems to be higher in people who have regular or ongoing depression with serious symptoms.


Can severe long-term depression cause brain damage?

Depression may cause the release of glucocorticoid in the brain, a type of steroid that can damage the hippocampus and other areas of the central nervous system. When this occurs, you may experience symptoms associated with neurocognitive disorder (dementia), such as memory loss.

Can long-term depression and anxiety cause brain damage?

Summary: Pathological anxiety and chronic stress lead to structural degeneration and impaired functioning of the hippocampus and the PFC, which may account for the increased risk of developing neuropsychiatric disorders, including depression and dementia.


Can your brain heal from depression?

Research suggests that some of the physical brain changes caused by depression can be reversed. A 2016 study showed that interventions, such as antidepressants and cognitive behavioral therapy, may help reduce inflammation caused by depression.

Is depression damage reversible?

Depression and mood disorders are characterized by structural as well as neurochemical alterations in the brain. However, these changes are not permanent, and can be blocked or reversed with behavioral and pharmacological treatments.


How Your Brain Works When You're Depressed | Better | NBC News



Can major depression be permanent?

Major depressive disorder isn't something that eventually “passes.” While most people feel sad at times in their lives, major depression is when a person is in a depressed mood most of the day, nearly every day, for at least two weeks.

What are signs of brain damage?

Danger signs in adults
  • Have a headache that gets worse and does not go away.
  • Experience weakness, numbness, decreased coordination, convulsions, or seizures.
  • Vomit repeatedly.
  • Have slurred speech or unusual behavior.
  • Have one pupil (the black part in the middle of the eye) larger than the other.


What are long term effects of having depression?

According to the Mayo Clinic, patients with untreated long-term depression are more prone to sleep disruptions, heart disease, weight gain or loss, weakened immune system, and physical pain. Depression can result in an unhealthy cycle.


What is it called when you've been depressed for years?

Overview. Persistent depressive disorder is a continuous, long-term form of depression. You may feel sad and empty, lose interest in daily activities and have trouble getting things done. You may also have low self-esteem, feel like a failure and feel hopeless.

Can you be depressed for 5 years?

In general, nearly everyone with depression has ongoing feelings of sadness, and may feel helpless, hopeless, and irritable. Without treatment, symptoms can last for many years. This condition is most often treated with medicine, therapy, or a combination of both.

What is considered long term depression?

Persistent depressive disorder is a type of depression. It's less severe than major depressive disorder — another type — but it's ongoing. It's defined as lasting at least two years in adults and at least one year in children and teens.


What brain damage is permanent?

While damage to the brain following a traumatic brain injury is permanent because damaged brain cells cannot regenerate or repair themselves, there is hope for functional recovery. This is because functions affected by TBI may be rewired and improved by healthy brain cells.

How do you test for brain damage?

A medical exam is the first step to diagnose a potential brain injury. Assessment usually includes a neurological exam. This exam evaluates thinking, motor function (movement), sensory function, coordination, eye movement, and reflexes. Imaging tests, including CT scans and MRI scans, cannot detect all TBIs.

Can the brain repair itself?

“The brain's ability to repair or replace itself is not limited to just two areas. Instead, when an adult brain cell of the cortex is injured, it reverts (at a transcriptional level) to an embryonic cortical neuron.


How many years can you have depression?

So how long do depressive episodes last? Usually, the depressive episode length ranges from six months to eight months, depending on the person. While some people may have depression that fades, others may struggle with depression on and off their whole life.

What happens if major depression is not treated?

People who are depressed are far more likely to have other chronic medical conditions, including cardiovascular disease, back problems, arthritis, diabetes, and high blood pressure, and to have worse outcomes. Untreated depression can even affect your immune response to some vaccines.

What is the average lifespan of someone with major depressive disorder?

The Impact of Major Depression on Overall Health

This difference in overall health, on average, translates to a reduction in future healthy life expectancy of 9.5 years for women and 9.7 years for men.


Can brain damage be detected years later?

Because injured brain tissue may not completely recover following TBI, changes due to TBI may be detectable many years after an injury.

Can you have brain damage and not know it?

Yes. Many people who have problems such as poor memory, difficulties in learning and behavioral issues are unaware they are experiencing symptoms resulting from an “unidentified” traumatic brain injury.

Can a damaged brain get better?

The brain does not fully mend itself the way a cut or other injury does in the body. Recovery and return to function following brain damage depends on the cause of the injury and the person's symptoms.


How do you check brain health?

Routine EEG — This type of EEG is used to measure the electrical activity of the brain. EEGs are performed to determine whether abnormal brainwaves are present, which can aid in the diagnosis of seizures as well as other neurologic disorders, including epilepsy.

Does brain damage ever get better?

Can the brain heal after being injured? Most studies suggest that once brain cells are destroyed or damaged, for the most part, they do not regenerate. However, recovery after brain injury can take place, especially in younger people, as, in some cases, other areas of the brain make up for the injured tissue.

Can you be depressed for ten years?

For some people, depression might only be episodic and overcome within a matter of weeks or months. However, for others diagnosed with major depression , the condition could persist for years, affecting their lifestyle and quality of life.


What is the depression that lasts for 2 years?

Dysthymia is long-term depression which lasts at least 2 years. It has similar symptoms to major depression, but they're less severe.

Can people with depression live a long life?

Depression on its own does not cause death but the behaviors associated with depressed individuals increases the risk of chronic and deadly diseases. These diseases may include coronary heart disease, obesity, diabetes, lung disease, osteoporosis, and cancer.