What food should I avoid while taking terbinafine?

Do not use applesauce or fruit-based foods. If you will need two packets of oral granules with each dose, you may sprinkle the content of both packets on one spoonful or two spoonfuls of non-acidic food. Avoid caffeine (coffee, soda, chocolate) while you are using this medicine.

What should I eat with terbinafine?

You can take terbinafine tablets with or without food. It's best to take your tablets at the same time each day.

What interferes with terbinafine?

Some products that may interact with this drug include: warfarin, drugs affecting liver enzymes that remove terbinafine from your body (such as amiodarone, cimetidine, rifampin, azole antifungals such as fluconazole/ketoconazole), drugs removed from your body by certain liver enzymes (such as tricyclic antidepressants, ...

Why can't you drink coffee with terbinafine?

You may need to limit your Caffeine intake while receiving Terbinafine tablets. Too much Caffeine can cause effects like nausea, nervousness, or sleeplessness. Terbinafine skin creams do not interact. Notes for Professionals: Terbinafine has been shown to inhibit the clearance of caffeine.

Should I take terbinafine in the morning or at night?

Timing: Take terbinafine tablets at the same time each day, either in the morning OR in the evening. You can take terbinafine with or without food. Missed dose: If you forget to take your dose, take it as soon as you remember that day.

Terbinafine - Mechanism of action, Side effects, and Indications [29/31]

Does terbinafine affect sleep?

Other symptoms include feeling very sad or empty, irritable, lack of appetite, loss of interest or pleasure, restlessness, trouble concentrating, or trouble sleeping. Serious skin reactions can occur with this medicine.

How common is liver damage from terbinafine?

Clinically apparent liver injury from terbinafine occurs rarely (1 in 50,000 to 120,000 prescriptions), but many case reports and even case series have been described in the literature. Liver injury usually arises within the first 6 weeks of therapy.

How do I know if terbinafine is affecting my liver?

Any symptoms of persistent nausea, anorexia, fatigue, vomiting, right upper abdominal pain or jaundice, dark urine, or pale stools must be reported. Patients with these symptoms should discontinue taking the drug, and the patient's liver function should be immediately evaluated.

When do terbinafine side effects start?

Taste disturbances were typically noticed 5 to 8 weeks after starting therapy and returned to normal within several weeks after stopping the medication. The taste alteration has been rarely accompanied by a discoloration of the tongue and/or a disturbance in the sense of smell.

Can I take vitamins while taking terbinafine?

Interactions between your drugs

No interactions were found between Lamisil and Vitamins. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

How long do I need to take terbinafine for toenail fungus?

For onychomycosis (fungus infections of the toenails): Adults—250 milligrams (mg) once a day for 12 weeks.

How long does it take for oral terbinafine to work on toenail fungus?

Lamisil comes as a tablet that you take by mouth. Lamisil Tablets are usually taken: 1 time each day for 6 weeks to treat fungal infections of your fingernail, or. 1 time each day for 12 weeks to treat fungal infections of your toenail.

Why is terbinafine hard on your liver?

Like many drugs, terbinafine is metabolised by the liver and excreted by the kidneys, consequently a reduction in function of either of those two organ systems could result in serious problems if prescribed to the wrong patient.

Can I take vitamin D with terbinafine?

Interactions between your drugs

No interactions were found between terbinafine and Vitamin D3. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

How long does it take for terbinafine pills to work?

Fungal nail infections usually take longer to heal than fungal skin infections. You will usually take the tablets for anywhere from 6 weeks to 3 months. But, if you have a nail infection of the big toe or your nails grow very slowly, you may need to take the tablets for up to 6 months.

How many months can you take terbinafine?

You will usually take the tablets for anywhere from 6 weeks to 3 months. But, if you have a nail infection of the big toe or your nails grow very slowly, you may need to take the tablets for up to 6 months.

Does terbinafine make you tired?

Some people taking terbinafine have developed severe liver damage leading to liver transplant or death. Call your doctor at once if you have symptoms of liver damage, such as nausea, upper stomach pain, vomiting, loss of appetite, tiredness, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Is weight gain a side effect of terbinafine?

swelling, rapid weight gain, little or no urinating; blood in your urine or stools; weight loss due to taste changes or loss of appetite; or. skin sores, butterfly-shaped skin rash on your cheeks and nose (worsens in sunlight).

What is the success rate of terbinafine?

Forty-eight percent achieved a clinical cure compared with only 6% of the placebo group (RR 6.00, 95% CI 3.96 to 9.08; 8 studies, 1,006 people). The mycological cure rate was 59% vs 17% with placebo (RR 4.53, 95% CI 2.47 to 8.33) though there was high variability between individual studies for this outcome.

Is it worth taking terbinafine?

Terbinafine has an average rating of 6.3 out of 10 from a total of 456 ratings on Drugs.com. 55% of reviewers reported a positive experience, while 33% reported a negative experience.

How common is liver damage with antifungals?

In a large meta-analysis of antifungals tolerability and hepatotoxicity, the risk of liver injury with standard dose of fluconazole not requiring treatment discontinuation was 9.3%, while the risk of drug discontinuation due to elevated liver enzymes was 0.7% [74].

Does toenail fungus come back after terbinafine?

A 7-year prospective study of 73 onychomycosis patients who were successfully treated (mycological and clinical cure) with continuous terbinafine or intermittent itraconazole showed that recurrence occurred at a mean time of 36 months after successful treatment [8].

How do you know if your liver is damaged from medication?

Is terbinafine hard on kidneys?

The clinical history combined with the diagnostic findings suggest acute kidney injury and rhabdomyolysis associated with terbinafine use.

Can I exercise while taking terbinafine?

Clinicians should consider advising patients to avoid intensifying exercise while using terbinafine. This effect may persist for weeks because of the terminal half-life of terbinafine being 2–4 weeks [18].