What interferes with levothyroxine?

A number of drugs have been shown to impair the absorption of levothyroxine; these drugs include calcium carbonate, aluminum- containing antacids, sucralfate, iron supplements, cholestyramine, sevelamer, and, possibly, ciprofloxacin, raloxifene, and orlistat.


What supplements should not be taken with levothyroxine?

As mentioned above, levothyroxine should not be taken within 4 hours of medications and supplements like antacids, bile acid sequestrants, ion exchange resins, iron supplements, or calcium.

What should you not take with thyroid medication?

Don't take calcium supplements or antacids at the same time you take thyroid hormone replacement. Take any products containing calcium at least four hours before or after taking thyroid hormone replacement.


What cancels out levothyroxine?

Many commonly used drugs, such as bile acid sequestrants, ferrous sulphate, sucralfate, calcium carbonate, aluminium-containing antacids, phosphate binders, raloxifene and proton-pump inhibitors, have also been shown to interfere with the absorption of levothyroxine.

What drinks interfere with levothyroxine?

Caffeine in coffee, tea, and other caffeinated beverages decreases the absorption of levothyroxine by causing the drug to move too quickly through the intestines before it has the chance to be absorbed.


Levothyroxine Use Dosage and Side Effects



How long do I have to wait to drink coffee after taking levothyroxine?

A new study conducted by Vertice Pharma confirms the absorption of an oral levothyroxine sodium solution (Thyquidity® 100g/ 5mL) was not affected by consuming coffee 5 minutes after the dose, according to research being presented Saturday at ENDO 2022, the Endocrine Society's annual meeting in Atlanta, Ga.

What happens if you drink coffee after taking levothyroxine?

Current product labels and treatment guidelines recommend patients take thyroid hormone replacement therapy on an empty stomach, but this new research shows that absorption of liquid levothyroxine is not affected by consuming coffee shortly after taking the medication.

What blocks thyroid medication?

Iron and calcium supplements can interfere with how your body absorbs thyroid medications. So space these at least 1 hour apart. Another supplement to watch out for is biotin. It's commonly taken for its hair, skin, and nail benefits.


Why can't you lay down after taking levothyroxine?

Official answer. There is no warning or instruction about lying down after you take levothyroxine in the drug's detailed prescribing information. Unless your doctor gives you different directions, you can lay down after taking it.

Do vitamins interfere with levothyroxine?

Using multivitamin with minerals together with levothyroxine may decrease the effects of levothyroxine. You should separate the administration of levothyroxine and multivitamin with minerals by at least 4 hours.

Why do you have to drink a full glass of water with levothyroxine?

Take the tablets with a full glass of water as they may get stuck in your throat or cause choking or gagging. If you are giving levothyroxine to an infant, child, or adult who cannot swallow the tablet, crush and mix it in 1 to 2 teaspoons (5 to 10 mL) of water.


Is it better to take levothyroxine at night or in the morning?

There is consensus that levothyroxine should be taken in the morning on an empty stomach. A pilot study showed that levothyroxine intake at bedtime significantly decreased thyrotropin levels and increased free thyroxine and total triiodothyronine levels.

What is the best vitamin to take with levothyroxine?

It's best to take a nutritional supplement that includes the entire vitamin B complex, and you may need additional vitamin B12 if a blood test reveals your levels are low, she says.

Why is it better to take levothyroxine at night?

However, in an additional analysis performed on nine studies, researchers found that levothyroxine administered at bedtime was associated with a higher free thyroxine (T4) level when compared with breakfast administration.


What happens if you take thyroid medicine after eating?

Taking it with or too soon before or after a meal or snack could reduce absorption to 64%, from a high of 80% when you're fasting, according to the American Thyroid Association. ³ Just changing your timing could bring your thyroid levels back into a normal range.

Does levothyroxine affect sleep?

No adverse effects were noted. Conclusions: After treatment with levothyroxine for over 4 weeks, prolonged sleep time and EDS were improved. Levothyroxine was effective for hypersomnia and well tolerated.

What blocks Synthroid absorption?

Foods like soybean flour, cottonseed meal, walnuts, and dietary fiber may cause your body to absorb less SYNTHROID from the gastrointestinal tract. Grapefruit juice may cause your body to absorb less levothyroxine and may reduce its effect.


Which fruit is best for thyroid?

Apples, pears, plums and citrus fruits are abundant with pectins, which help with detoxifying the body of mercury – one of the most critical metals that have been connected to thyroid problems.

Should I take thyroid medication at night?

Official answer. Yes, you can take your thyroid medication at night, as long as you are taking it on an empty stomach.

Does levothyroxine make you tired?

Extreme tiredness is a commonly reported side effect of Levothyroxine. Many people begin treatment but feel no better after starting medication, which may be because they are experiencing this effect. You feel more tired while taking Levothyroxine because the hormones in your body have been effectively reduced.


What is the difference between Synthroid and levothyroxine?

What's the difference between levothyroxine and Synthroid? Levothyroxine and Synthroid contain the same active (main) ingredient, levothyroxine, which is human-made T4. Levothyroxine is the generic name for Synthroid.

Can you eat dairy after taking levothyroxine?

“The main message of this study is that patients managed with thyroid hormone replacement therapy should be advised to avoid taking levothyroxine simultaneously with cow's milk, given its interference,” Chon said. Primary Source: Concurrent Milk Ingestion Decreases Oral Levothyroxine Absorption.

Can levothyroxine cause weight gain?

Does Levothyroxine Cause Weight Gain? Both weight gain and weight loss are possible side effects. Many people do not take the right dosage of levothyroxine, and both undertreatment and overtreatment can have an effect on weight. Levothyroxine weight gain may be tied to undertreatment, according to the ATA.


Can I take vitamin D and B12 with levothyroxine?

Interactions between your drugs

No interactions were found between levothyroxine and Vitamin B12.

How can I boost my thyroid naturally?

Thyroid Superfoods
  1. Roasted seaweed. Seaweed, such as kelp, nori, and wakame, are naturally rich in iodine--a trace element needed for normal thyroid function. ...
  2. Salted nuts. Brazil nuts, macadamia nuts, and hazelnuts are excellent sources of selenium, which helps support healthy thyroid function. ...
  3. Baked fish. ...
  4. Dairy. ...
  5. Fresh eggs.