What is the least problematic statin?

According to a research review people who take simvastatin (Zocor) or pravastatin (Pravachol) may experience fewer side effects.


Which type of statin has least side effects?

In the analysis of 135 previous studies, which included nearly 250,000 people combined, researchers found that the drugs simvastatin (Zocor) and pravastatin (Pravachol) had the fewest side effects in this class of medications.

Which statin is most well tolerated?

Serious adverse events are very rare. Among the individual medications, studies have shown that simvastatin (Zocor®) and pravastatin (Pravachol®) seem to be safer and better tolerated than the other statins.


What is the safest statin for your liver?

In a retrospective cohort study, lovastatin showed no increased risk of adverse hepatic effects in a total of 93,106 patients with liver disease.

Which statin has the most amount of side effects?

It's possible, although unlikely, that one particular statin may cause side effects for you while another statin won't. It's thought that simvastatin (Zocor) may be more likely to cause muscle pain as a side effect than other statins when it's taken at high doses.


Study Confirms What Many Patients Taking Statins Have Said for Years | NBC Nightly News



Is there a new statin without side effects?

Another newer option is actually a statin. It's called pitavastatin, or Livalo. It has the same LDL- and total cholesterol-lowering property as all the other statins, but somehow doesn't give the muscle aches. A lot of people have had a lot of success taking this over any of the other statins out there.

What is the number one statin?

Rosuvastatin and atorvastatin are the best at lowering LDL cholesterol.

What is the easiest statin to tolerate?

According to a research review people who take simvastatin (Zocor) or pravastatin (Pravachol) may experience fewer side effects.


How long does it take for statins to damage liver?

Statin-associated hepatocellular injury frequently occurs 5 to 90 days after the initiation of therapy. Bilirubin levels more than twice the ULN imply severe hepatocellular liver injury with a mortality of 10% and an incidence of 0.7–1.3 per 100,000 cases of drug-induced liver injury (DILI).

Can you get off statins once you start?

If you're taking a statin medication to lower your cholesterol, you will need to keep taking your prescription, or your cholesterol will likely go back up. Stopping your statin can put you at risk of having heart disease and other preventable health problems like stroke and heart attack from high cholesterol.

Which statin is least likely to cause muscle weakness?

Is muscle pain a side effect of all statins? Even though all statins are similar chemically, they have some minor differences that could impact how likely they are to cause muscle pain. Simvastatin is the most likely to cause muscle pain, and fluvastatin is the least likely.


What is the first drug of choice for cholesterol?

Statins are the most common medicine for high cholesterol. They reduce the amount of cholesterol your body makes. You take a tablet once a day. You usually need to take them for life.

Which statin causes the least joint pain?

Try a different statin

These statins, including atorvastatin (Lipitor®), simvastatin (Zocor®) and fluvastatin (Lescol®), are more likely to cause muscle aches. The hydrophilic statins, including rosuvastatin (Crestor®) and pravastatin (Pravachol®), have to be actively transported and cause fewer muscle aches.

Which statin is safest for kidneys?

Atorvastatin Has a Dose‐Dependent Beneficial Effect on Kidney Function and Associated Cardiovascular Outcomes: Post Hoc Analysis of 6 Double‐Blind Randomized Controlled Trials.


What can I take instead of statins to lower cholesterol?

7 cholesterol-lowering alternatives to statins
  • Fibrates. Mostly used for lowering triglyceride levels in patients whose levels are very high and could cause pancreatitis. ...
  • Plant stanols and sterols. ...
  • Cholestyramine and other bile acid-binding resins. ...
  • Niacin. ...
  • Policosanol. ...
  • Red yeast rice extract (RYRE) ...
  • Natural products.


Why do statins have to be taken at night?

So, why do people take statins at night? Many statins work more effectively when they are taken at night. This is because the enzyme which makes the cholesterol is more active at night. Also, the half-life, or the amount of time it takes for half the dose to leave your body, of some statins is short.

Can statins reverse fatty liver?

There are no specific treatments for NAFLD, but cholesterol-lowering drugs called statins appear to slow its progression to more serious liver inflammation and fibrosis/scarring, characteristics of NASH.


Which is safer Lipitor or Crestor?

Despite this, there was no significant difference between the two drugs in how well they decreased the volume of atherosclerotic buildup in the arteries. Both Crestor and Lipitor are generally well tolerated with a similar rate of side effects.

Which statin is best to start with?

The synthetic and natural statins have essentially equivalent efficacy at improving the lipid profile. However, in patients who do not achieve their LDL goals, atorvastatin and simvastatin may be the best choices for initial therapy.

Which is safer atorvastatin or rosuvastatin?

In relation to renal function, atorvastatin was the safest statin as it resulted in the least number of patients at the end of 2 years of treatment with the new onset of microalbuminuria (10.9%) followed by rosuvastatin (14.3%) and then pravastatin (26.6%). Conclusion.


Is there a better statin than Lipitor?

They looked at the effects of Lipitor, Crestor, Zocor, and Pravachol on lowering LDL (low-density lipoprotein) cholesterol after six weeks. The study concluded that Crestor lowered LDL cholesterol by 8.2% more than Lipitor, and Crestor lowered total cholesterol significantly more than all the other statins studied.

Which statin lowers LDL the most?

Similarly, data from comparative trials, shown in Table 1 confirm that rosuvastatin is the most effective statin for lowering LDL-C (reduction of 63% with 40 mg daily), followed by atorvastatin, simvastatin, and pravastatin. The lipid lowering effect of pitavastatin was comparable to atorvastatin.

Is there a better solution than statins?

Along with a healthy diet and exercise, statin alternatives like ezetimibe (Zetia) can be taken with or without statins to help you meet your cholesterol goals. Natural and over-the-counter medications, like fish oil supplements, may also help manage your cholesterol levels.


Why was Lipitor taken off the market?

Type 2 diabetes -- Lipitor may increase your blood sugar, which could lead to the development of type 2 diabetes. Even though the risk is low, the Food & Drug Administration (FDA) considered it serious enough to include a warning regarding raised blood sugar and diabetes on all statin medication.

What is a natural alternative to statin drugs?

For patients who can't tolerate cholesterol-lowering statins, natural remedies like bergamot, garlic and green tea may be a useful alternative, based on a recent statement published in the Journal of the American College of Cardiology.