What is the most serious side effect of atorvastatin?

Serious side effects
you get unexplained muscle pain, tenderness, weakness or cramps – these can be signs of muscle breakdown and kidney damage.


What damage can atorvastatin cause?

summarized several forms of side effects attributed to the use of atorvastatin, including hepatocellular injury, cholestatic injury, mixed pattern of atorvastatin-associated hepatocellular and cholestatic injury, autoimmune-type reaction and fulminant liver failure [2].

Who should not take atorvastatin?

Atorvastatin is not approved for use by anyone younger than 10 years old.
...
Tell your doctor if you have ever had:
  • liver problems;
  • muscle pain or weakness;
  • kidney disease;
  • diabetes;
  • a thyroid disorder; or.
  • if you drink more than 2 alcoholic beverages daily.


Do atorvastatin side effects go away?

Most side effects caused by Lipitor are mild and typically go away on their own. However, there are some rare but serious side effects reported by people using the drug in clinical trials. These include myopathy, rhabdomyolysis, and liver damage.

Why would a doctor stop atorvastatin?

Dr. Carimi says muscle-related complications are the most common side effect from taking statins. “The most common reason people stop taking statins is because of side effects, like muscle aches, but many have muscle pains from other causes and stop taking the medication in error,” Dr. Carimi says.


Statin Side Effects | Atorvastatin, Rosuvastatin, Simvastatin Side Effects & Why They Occur



What drug can replace atorvastatin?

  • Other alternatives to atorvastatin.
  • Other HMG CoA Reductase Inhibitors (statins) such as: Crestor (rosuvastatin), Zocor (simvastatin), Pravachol (pravastatin), or Mevachor (lovastatin)
  • Colestid (colestipol)
  • Tricor (fenofibrate)
  • Zetia (ezetimibe)
  • WelChol (colesevelam)


How long can you stay on atorvastatin?

The benefit of high-dose atorvastatin has been sustained for at least 5 years. Conclusion: After an ACS, high-dose atorvastatin should be continued for at least 5 years. High-dose atorvastatin demonstrated a reduction in coronary events but dose reductions and higher discontinuation rates were also noted.

Can you take a break from atorvastatin?

You will not get any withdrawal symptoms. However, stopping atorvastatin may cause your cholesterol to rise. This increases your risk of heart attacks and strokes. If you want to stop taking your medicine, it's important to find another way to lower your cholesterol.


What does pain from atorvastatin feel like?

One of the most common complaints of people taking statins is muscle pain. You may feel this pain as a soreness, tiredness or weakness in your muscles. The pain can be a mild discomfort, or it can be severe enough to make your daily activities difficult.

What is the best statin with the least side effects?

According to a research review people who take simvastatin (Zocor) or pravastatin (Pravachol) may experience fewer side effects.

What should I watch for atorvastatin?

Call your doctor right away if you have dark-colored urine, fever, muscle cramps or spasms, muscle pain or stiffness, or unusual tiredness or weakness. These could be symptoms of a serious muscle problem called rhabdomyolysis, which can cause kidney problems.


Why should people over 70 not take atorvastatin?

Compared to younger adults, older adults are more likely to suffer serious side effects from using statins. Statins can cause muscle problems, such as aches, pains, or weakness. Rarely, there can be a severe form of muscle breakdown.

When should I stop taking atorvastatin?

You may want to stop atorvastatin if you think you're having side effects. Talk to your doctor first to see if it really is a side effect of atorvastatin or an unrelated problem. Your doctor may decide to lower your dose or change your medicine. You will not get any withdrawal symptoms.

Does atorvastatin affect the brain?

Statins have been linked to short-term reversible cognitive impairment since early safety and tolerability testing [13]. During a phase I clinical trial of atorvastatin, escalating doses showed a dose-dependent adverse reaction of mild, transient, restlessness, euphoria, and mental confusion [13].


What are the two most common adverse effects of statins?

Side effects can vary between different statins, but common side effects include: headache. dizziness.

What happens when you go off statins?

Statins work to lower cholesterol levels and can reduce the risk of heart disease, heart attack, stroke, and even cardiovascular disease deaths by 25% or more. It's important to note that if you stop taking them, these improved effects on your cholesterol will taper off after several months.

How do you stop statin muscle pain?

Although there are no proven remedies for statin-related muscle pain, the following may help.
  1. Exercise. ...
  2. Ramp up your lifestyle changes. ...
  3. Have a thyroid blood test. ...
  4. Take supplements. ...
  5. Change your prescription. ...
  6. Image: © Christophe Bourloton/Thinkstock.


Which muscles are most affected by statins?

Within a month of starting statin therapy, they may feel aches or weakness in the large muscles of their arms, shoulders, thighs or buttocks on both sides of the body. About 5 to 10% of people who try statins are affected. It's more common in the elderly, in women and in those taking the more potent statins.

Can you get off statins once you start?

If you're taking a statin medication to lower your cholesterol, you will need to keep taking your prescription, or your cholesterol will likely go back up. Stopping your statin can put you at risk of having heart disease and other preventable health problems like stroke and heart attack from high cholesterol.

What happens if you take atorvastatin every other day?

Atorvastatin every other day significantly reduced total cholesterol (TC), triglyceride (TG), and LDL-c versus baseline. The TC, TG, and LDL-c levels were lower by 23 per cent, 8 per cent, and 30 per cent. Increase in HDL-c level was not statistically significant.


Do I need to take atorvastatin for life?

Check with your doctor whether there's a particular time of day you should take your statin. You usually have to continue taking statins for life because if you stop taking them, your cholesterol will return to a high level.

What happens if I miss my statins for a few days?

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Do not take 2 doses of this medicine if it has been more than 12 hours since you missed your last dose.

What can I take instead of statins to lower cholesterol?

7 cholesterol-lowering alternatives to statins
  • Fibrates. Mostly used for lowering triglyceride levels in patients whose levels are very high and could cause pancreatitis. ...
  • Plant stanols and sterols. ...
  • Cholestyramine and other bile acid-binding resins. ...
  • Niacin. ...
  • Policosanol. ...
  • Red yeast rice extract (RYRE) ...
  • Natural products.


Does atorvastatin affect sleep?

The current evidence, from well-run research trials of more than 100,000 patients, is that statins do not cause insomnia or any other sleep disturbance, compared with a dummy pill (placebo).

Is atorvastatin a lifelong drug?

Taking statins is often (but not always) a lifelong commitment. Even if your cholesterol levels decrease, you may still need to take the medication. Otherwise, your levels will likely go back up once you're off the medication.
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