What medications can cause pancreatitis?

Class II medications (medications implicated in more than 10 cases of acute pancreatitis): rifampin, lamivudine, octreotide, carbamazepine, acetaminophen, phenformin, interferon alfa-2b, enalapril, hydrochlorothiazide, cisplatin, erythromycin, and cyclopenthiazide.


Which drug is most likely to cause pancreatitis?

5,6 The most common drug associated with pancreatitis is alco- hol. Other offending drugs include azathioprine, furosemide, hydrochlorothiazide, estrogens, and sulfasalazine.

What medications bring on pancreatitis?

Medicines That Can Cause Pancreatitis
  • Antibiotics.
  • Drugs that suppress the immune system .
  • Drugs used to treat high blood pressure.
  • Aminosalicylates.
  • Diuretics .
  • Corticosteroids .
  • Estrogen .
  • Drugs used to treat diabetes .


What drugs damage the pancreas?

The most pronounced substance abuse damage to the pancreas is done through alcohol abuse, but damage can also be caused by heroin, cocaine and prescription drug abuse. Heavy consumption of alcohol causes the pancreas to stop secreting digestive enzymes.

What are the two most common causes of pancreatitis?

It may be sudden (acute) or ongoing (chronic). The most common causes are alcohol abuse and lumps of solid material (gallstones) in the gallbladder.


Drugs Causing Pancreatitis Mnemonic for USMLE Step 1



What is the number one symptom of pancreatitis?

The main symptom of pancreatitis is pain felt in the upper left side or middle of the abdomen. The pain: May be worse within minutes after eating or drinking at first, more commonly if foods have a high fat content. Becomes constant and more severe, lasting for several days.

What are the warning signs of pancreatitis?

Acute pancreatitis signs and symptoms include:
  • Upper abdominal pain.
  • Abdominal pain that radiates to your back.
  • Tenderness when touching the abdomen.
  • Fever.
  • Rapid pulse.
  • Nausea.
  • Vomiting.


What blood pressure meds cause pancreatitis?

Losartan is a commonly prescribed angiotensinogen receptor blocker used for controlling blood pressure. Drug-induced acute pancreatitis is a rare side-effect associated with this medication and the primary means of its diagnosis is by the exclusion of the common causes of pancreatitis.


What are 3 diseases to affect pancreas?

There are a variety of disorders of the pancreas including acute pancreatitis, chronic pancreatitis, hereditary pancreatitis, and pancreatic cancer.

Can medication cause problems with pancreas?

In certain cases, medicines may cause inflammation of the pancreas (pancreatitis). These include: Antibiotics. Medicines that suppress the immune system.

What is the fastest way to cure pancreatitis?

Mild acute pancreatitis usually goes away in a few days with rest and treatment. If your pancreatitis is more severe, your treatment may also include: Surgery. Your doctor may recommend surgery to remove the gallbladder, called cholecystectomy, if gallstones cause your pancreatitis.


What is the best thing to do for pancreatitis?

Lifestyle changes
  • Avoiding alcohol. The most important thing you can do is stop drinking alcohol, even if it isn't the cause of your condition. ...
  • Stopping smoking. If you smoke, you should stop. ...
  • Dietary changes. Because chronic pancreatitis can affect your ability to digest certain foods, you may need to change your diet.


How can I get immediate relief from pancreatitis?

How can you care for yourself at home?
  1. Drink clear liquids and eat bland foods until you feel better. ...
  2. Eat a low-fat diet until your doctor says your pancreas is healed.
  3. Do not drink alcohol. ...
  4. Be safe with medicines. ...
  5. If your doctor prescribed antibiotics, take them as directed. ...
  6. Get extra rest until you feel better.


What can cause a flare up of pancreatitis?

Pancreatitis happens when your pancreas becomes irritated and inflamed (swollen). It's not a common condition. There are multiple causes, but the main culprits are gallstones or heavy alcohol use. The condition can flare up suddenly or be a long-lasting problem, which can lead to permanent damage.


How common is drug induced pancreatitis?

Drugs are a relatively rare cause of acute pancreatitis, with an estimated incidence of 0.1-2%. Many drugs have been suspected of causing pancreatitis, but the true incidence is not known as the evidence is derived mainly from random case reports.

What medications cause pancreatitis uptodate?

Pancreatitis is possibly caused by azathioprine, furosemide (frusemide), tetracycline, metronidazole, isoniazid, rifampicin (rifampin), sulphonamides, cyclosporin and some antineoplastic drugs.

What are signs that your pancreas is not working properly?

Symptoms of chronic pancreatitis

Constant pain in your upper belly that radiates to your back. This pain may be disabling. Diarrhea and weight loss because your pancreas isn't releasing enough enzymes to break down food. Upset stomach and vomiting.


What are four causes of pancreatitis?

What causes pancreatitis?
  • gallstones.
  • heavy alcohol use.
  • genetic disorders of your pancreas.
  • some medicines.


What are the stages of pancreatitis?

Pancreatitis has two stages — acute and chronic. Chronic pancreatitis is a more persistent condition. Most cases of acute pancreatitis are mild and involve a short hospital stay for the pancreas to recover. Acute pancreatitis occurs suddenly after the pancreas is damaged.

Which statins can cause pancreatitis?

Of the several medications that may cause pancreatitis, statin induced pancreatitis has become increasingly common. There have been several case reports of statin induced pancreatitis, and they have been associated with the use of simvastatin, pravastatin, fluvastatin, and more recently atorvastatin.


What medications can cause elevated pancreatic enzymes?

Some of the more common culprits for DIP include valproic acid, calcium-channel blockers, antipsychotic agents, sulindac (Clinoril, Merck), methyldopa, octreotide (Sandostatin, Novartis), 6-mercaptopurine, 5-aminosalicylic acid compounds, metronidazole (Flagyl, Pfizer), isoniazid, and corticosteroids.

Which diabetes medication can cause pancreatitis?

Some diabetes medications may increase the risk of pancreatitis. In particular, the class of medications that target glucagon-like peptide-1 (GLP-1) to control blood sugar levels have been linked to the increased risk. The drugs Januvia (sitagliptin) and Byetta (exenatide) fall into this category.

What are red flags for pancreatitis?

The most common symptoms of acute pancreatitis include: suddenly getting severe pain in the centre of your tummy (abdomen) feeling or being sick. a high temperature of 38C or more (fever)


When should you suspect pancreatitis?

Signs and Symptoms

Almost everyone with acute pancreatitis has severe and constant abdominal pain in the upper abdomen, below the sternum. The pain penetrates to the back in about 50% of people. With gallstones, the pain usually starts suddenly and reaches its maximum intensity in minutes.

Does pancreatitis happen suddenly?

Acute pancreatitis occurs suddenly and usually goes away in a few days with treatment. It is often caused by gallstones. Common symptoms are severe pain in the upper abdomen, nausea, and vomiting.
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