What meds put you at risk for osteoporosis?

Certain anticonvulsants may cause bone loss. The medications most commonly associated with osteoporosis include phenytoin, phenobarbital, carbamazepine, and primidone. These antiepileptic drugs (AEDs) are all potent inducers of CYP-450 isoenzymes.


What medications increase the risk of osteoporosis?

Many drugs can affect bone metabolism. As examples, heparin, warfarin, cyclosporine, glucocorticoids, medroxyprogesterone acetate, cancer drugs, and thyroid hormone can cause bone loss, whereas thiazide diuretics can minimize bone loss [1,2]. This topic will review the skeletal effects of some of these drugs.

What medications weaken bones?

  • High doses of corticosteroids.
  • High doses of thyroid medicines.
  • Medicines that reduce levels of sex hormones.
  • Certain diabetes medicines.
  • Certain stomach medicines, such as proton pump inhibitors or antacids containing aluminum.
  • Certain antidepressants.
  • Mood stabilizers containing lithium.


What medication category creates a risk for decreased bone density?

While glucocorticoids (GCs) are most commonly associated with drug-induced osteoporosis, the use of several other therapeutic agents increase the risk of significant bone loss and fracture.

What is the strongest risk factor for osteoporosis?

The fall in estrogen levels in women at menopause is one of the strongest risk factors for developing osteoporosis.


Osteoporosis: Which Medications Increase Risk?



What are the two medications that may cause osteoporosis after long term use?

Several medicines can cause bone loss if used over the long term (several years). Some common ones include: Glucocorticoids, also called steroids, such as cortisone and prednisone.

What is the fastest way to increase bone density?

Weight-bearing exercises, such as walking, jogging, and climbing stairs, can help you build strong bones and slow bone loss.

What is the safest bone density medication?

Bisphosphonates are usually the first choice for osteoporosis treatment. These include: Alendronate (Fosamax), a weekly pill. Risedronate (Actonel), a weekly or monthly pill.


Can blood pressure medicine cause osteoporosis?

Antihypertensive drugs impact osteoporosis directly and indirectly by affecting bone metabolism, strength and density (3). Meta- and epidemiological analyses of national databases illustrate an association between antihypertensive drugs and bone function (4-7).

What medications deplete calcium?

Medications that can cause low calcium levels

Your calcium levels can become low with tablets like ibandronate (Boniva) and alendronate (Fosamax). But it's more likely to happen with high doses of strong bisphosphonates, like zoledronic acid (Reclast), a medication given intravenously (IV).

What vitamins weaken bones?

A Tufts University study done by Katherine Tucker and her colleagues showed that low levels of vitamin B12 are linked to a higher risk of osteoporosis in both men and women. Vitamin B12 is found in meat and fish, making vegans, who don't eat meat or dairy, at risk for bone loss.


What vitamin causes weak bones?

Vitamin D deficiency can lead to a loss of bone density, which can contribute to osteoporosis and fractures (broken bones). Severe vitamin D deficiency can also lead to other diseases. In children, it can cause rickets. Rickets is a rare disease that causes the bones to become soft and bend.

What foods leach calcium from bones?

Animal protein—in fish, poultry, red meat, eggs, and dairy products—tends to leach calcium from the bones and encourages its passage into the urine. Plant protein—in beans, grains, and vegetables—does not appear to have this effect.

What should be taken daily to avoid osteoporosis?

Prevention of osteoporosis
  1. have a healthy and varied diet with plenty of fresh fruit, vegetables and whole grains.
  2. eat calcium-rich foods.
  3. absorb enough vitamin D.
  4. avoid smoking.
  5. limit alcohol consumption.
  6. limit caffeine.
  7. do regular weight-bearing and strength-training activities.


Does Tylenol cause osteoporosis?

There are other drugs that have limited scientific evidence for affecting fracture risk. These include: 1. The use of acetaminophen (e.g. Tylenol®) for a period of at least 3 years (dose uncertain) compared to non-users has been associated with an increased risk of fracture.

What are five risk factors for osteoporosis?

Factors that will increase the risk of developing osteoporosis are:
  • Female gender, Caucasian or Asian race, thin and small body frames, and a family history of osteoporosis. ...
  • Cigarette smoking, excessive alcohol and caffeine consumption, lack of exercise, and a diet low in calcium.
  • Poor nutrition and poor general health.


Do beta blockers cause osteoporosis?

No association was seen between the duration of beta blocker use and differences in bone mineral density, but dosage did have an impact. The effect size increased with dose level at low to intermediate dosages but then appeared to level off or decrease at higher doses.


Does omeprazole cause osteoporosis?

Yang et al. 4 stated that using PPIs could cause deleterious effects in bone tissue and could increase the risk of osteoporotic fractures, especially after four years of continual use. Vestergaard et al. 21 corroborated the previous study and confirmed the relationship between PPI use and osteoporotic fractures.

Does gabapentin cause osteoporosis?

Our data suggested that gabapentin induced the rarefaction of cancellous bone, which was associated with decreased bone formation and enhanced bone resorption, and may affect bone strength and BMD after chronic exposure.

Why was Fosamax taken off the market?

In 2010, the FDA convened a panel to review the increasing number of reports of Fosamax-related spontaneous fractures. After reviewing the research, the panel found a clear connection between Fosamax and spontaneous thigh bone fractures. The FDA then ordered Merck to change the label.


How can I reverse my osteoporosis?

The short answer is no, osteoporosis cannot be completely reversed and is not considered curable, but there are a number of health and lifestyle adjustments you can make to improve bone loss. Your provider may also prescribe you medications to help rebuild and slow down bone loss.

How can I increase my bone density after 60?

How can I keep my bones strong as I age?
  1. Eat foods that support bone health. Get enough calcium, vitamin D, and protein each day. ...
  2. Get active. Choose weight-bearing exercise, such as strength training, walking, hiking, jogging, climbing stairs, tennis, and dancing. ...
  3. Don't smoke. ...
  4. Limit alcohol consumption.


Is Oatmeal good for osteoporosis?

Oats are also believed to be the best whole grain to consume when it comes to preventing osteoporosis. The combination of minerals within oats makes them great for promoting bone mineral density.


What is the best exercise for bone density?

Weight-bearing and resistance exercises are the best for your bones. Weight-bearing exercises force you to work against gravity. They include walking, hiking, jogging, climbing stairs, playing tennis, and dancing. Resistance exercises – such as lifting weights – can also strengthen bones.

How can I restore bone density naturally?

Keep reading for tips on increasing bone density naturally.
  1. Weightlifting and strength training. ...
  2. Eating more vegetables. ...
  3. Consuming calcium throughout the day. ...
  4. Eating foods rich in vitamins D and K. ...
  5. Maintaining a healthy weight. ...
  6. Avoiding a low calorie diet. ...
  7. Eating more protein. ...
  8. Eating foods rich in omega-3 fatty acids.