Which drugs that cause osteoporosis most commonly?

Glucocorticoids are the drugs causing osteoporotic fractures most frequently, but osteoporosis with fractures is observed also in women treated with aromatase inhibitors for breast cancer, in men receiving anti-androgen therapy for prostate cancer, in postmenopausal women treated with high doses of thyroxine, and in ...


What drugs cause osteoporosis?

Many drugs can affect bone metabolism. As examples, heparin, warfarin, cyclosporine, glucocorticoids, medroxyprogesterone acetate, cancer drugs, and thyroid hormone can cause bone loss, whereas thiazide diuretics can minimize bone loss [1,2]. This topic will review the skeletal effects of some of these drugs.

What drugs worsen osteoporosis?

Loop diuretics like furosemide (Lasix) and bumetanide (Bumex) can reduce the amount of calcium in your bones. these types of drugs have been shown to lower bone density in some studies of men and women. They may also increase the risk of bone fractures, according to some (but not all) studies.


What is the most common cause of osteoporosis?

Osteoporosis is more likely to occur in people who have: Low calcium intake. A lifelong lack of calcium plays a role in the development of osteoporosis. Low calcium intake contributes to diminished bone density, early bone loss and an increased risk of fractures.

What medications weaken bones?

  • High doses of corticosteroids.
  • High doses of thyroid medicines.
  • Medicines that reduce levels of sex hormones.
  • Certain diabetes medicines.
  • Certain stomach medicines, such as proton pump inhibitors or antacids containing aluminum.
  • Certain antidepressants.
  • Mood stabilizers containing lithium.


Osteoporosis Medications and Management | Which Drugs Are Used To Treat Osteoporosis?



What is the best medication to prevent osteoporosis?

Bisphosphonates are usually the first choice for osteoporosis treatment. These include: Alendronate (Fosamax), a weekly pill. Risedronate (Actonel), a weekly or monthly pill.

Does Tylenol cause osteoporosis?

There are other drugs that have limited scientific evidence for affecting fracture risk. These include: 1. The use of acetaminophen (e.g. Tylenol®) for a period of at least 3 years (dose uncertain) compared to non-users has been associated with an increased risk of fracture.

Why was Fosamax taken off the market?

In 2010, the FDA convened a panel to review the increasing number of reports of Fosamax-related spontaneous fractures. After reviewing the research, the panel found a clear connection between Fosamax and spontaneous thigh bone fractures. The FDA then ordered Merck to change the label.


What are the 5 causes of osteoporosis?

Osteoporosis Causes
  • Diet. Your diet has a significant impact on the health of your bones. ...
  • Exercise. Exercise is an essential defense against osteoporosis. ...
  • Low Sex Hormones. When women reach menopause, their estrogen levels drop significantly. ...
  • Medical Conditions. ...
  • Medications. ...
  • Smoking and Alcohol.


What is the most common and frequent symptom of osteoporosis?

Osteoporosis means that you have less bone mass and strength. The disease often develops without any symptoms or pain, and it is usually not discovered until the weakened bones cause painful fractures. Most of these are fractures of the hip, wrist and spine.

Can blood pressure medicine cause osteoporosis?

Antihypertensive drugs impact osteoporosis directly and indirectly by affecting bone metabolism, strength and density (3). Meta- and epidemiological analyses of national databases illustrate an association between antihypertensive drugs and bone function (4-7).


What are the four main types of drugs to prevent or treat osteoporosis?

Ibandronate (Boniva™) Zoledronic acid (Reclast™) Denosumab (Prolia™) Estrogen therapy or hormone therapy.

What should be taken daily to avoid osteoporosis?

Prevention of osteoporosis
  1. have a healthy and varied diet with plenty of fresh fruit, vegetables and whole grains.
  2. eat calcium-rich foods.
  3. absorb enough vitamin D.
  4. avoid smoking.
  5. limit alcohol consumption.
  6. limit caffeine.
  7. do regular weight-bearing and strength-training activities.


Does statin cause osteoporosis?

In the general population, statin use was associated with a three-fold higher rate of osteoporosis than controls (OR: 3.62, 95% CI 3.55 to 3.69, p<0.01).


Does drug use cause osteoporosis?

Abstract. Drug-induced osteoporosis is common and has a significant impact on the prognosis of patients suffering from chronic debilitating diseases.

Which antidepressants cause osteoporosis?

Selective serotonin reuptake inhibitors (SSRIs) account for approximately 62% of all antidepressants prescribed in the United States. There have been several recent studies suggesting that SSRIs may lower bone mineral density in individuals over the age of 65.

What is the fastest way to increase bone density?

Weight-bearing exercises, such as walking, jogging, and climbing stairs, can help you build strong bones and slow bone loss.


What lack of mineral causes osteoporosis?

Beginning in childhood and into old age, a diet low in calcium and vitamin D can increase your risk for osteoporosis and fractures. Excessive dieting or poor protein intake may increase your risk for bone loss and osteoporosis.

What are 2 risk factors for osteoporosis?

Osteoporosis Risk Factors
  • Gender. Your chances of developing osteoporosis are greater if you are a woman. ...
  • Age. The older you are, the greater your risk of osteoporosis. ...
  • Body size. Small, thin-boned women are at greater risk.
  • Ethnicity. Caucasian and Asian women are at highest risk. ...
  • Family history.


What dentists say about Fosamax?

Nevertheless, Sedghizadeh notes that USC now warns all dental patients taking Fosamax and other bisphosphonates that "you may be at risk of developing osteonecrosis (bone death) of the jaw, and certain dental treatments may increase that risk."


What is the newest treatment for osteoporosis?

Romosozumab (Evenity).

This is the newest bone-building medication to treat osteoporosis. It is given as an injection every month at your doctor's office and is limited to one year of treatment.

What is a natural alternative to Fosamax?

Calcium. Calcium is likely one of the most important supplements you can take when you have osteoporosis. Taking calcium is recommended by the Endocrine Society for most women undergoing osteoporosis treatment.

Can you reverse osteoporosis?

The short answer is no, osteoporosis cannot be completely reversed and is not considered curable, but there are a number of health and lifestyle adjustments you can make to improve bone loss. Your provider may also prescribe you medications to help rebuild and slow down bone loss.


Which form of calcium is best for osteoporosis?

What Is the Best Form of Calcium to Take for Osteoporosis?
  • Calcium carbonate, found in over-the-counter antacids, is a cheap and effective calcium source. ...
  • Calcium citrate is slightly more expensive, but it is more easily absorbed by the body, especially in older people.


Which vitamin helps osteoporosis the most?

Vitamin D plays an important role in protecting your bones, both by helping your body absorb calcium and by supporting muscles needed to avoid falls. Children need vitamin D to build strong bones, and adults need it to keep their bones strong and healthy.