Is Voltaren gel hard on the liver?

3) Diclofenac (Voltaren, Cambia)

Any NSAID (non-steroidal anti-inflammatory drug) can cause liver injury, although it's very rare. This class of medications includes popular drugs like ibuprofen and naproxen. But when it comes to liver injury, diclofenac is the NSAID with the highest risk.

Can diclofenac gel cause liver damage?

Therapy with diclofenac in full doses is frequently associated with mild serum aminotransferase elevations and, in rare instances, can lead to serious clinically apparent, acute or chronic liver disease.

Does Voltaren gel go into the bloodstream?

As a topical gel, a smaller amount of diclofenac from Voltaren Arthritis Pain Gel reaches the bloodstream compared with the oral form of diclofenac. In a clinical study, the systemic exposure with Voltaren Arthritis Pain Gel was 6%, or 94% less than the systemic exposure with the oral NSAID diclofenac.

What are the dangers of using Voltaren gel?

Who should not use Voltaren Gel?

If you are pregnant, you should not use Voltaren Arthritis Pain gel unless your doctor tells you to. Using a NSAID during the last 20 weeks of pregnancy can cause serious heart or kidney problems in the unborn baby and possible complications with your pregnancy.

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Does Voltaren hurt your liver?

3) Diclofenac (Voltaren, Cambia)

Any NSAID (non-steroidal anti-inflammatory drug) can cause liver injury, although it's very rare. This class of medications includes popular drugs like ibuprofen and naproxen. But when it comes to liver injury, diclofenac is the NSAID with the highest risk.

Is Voltaren gel hard on the kidneys?

You should also know that long-term NSAID use can lead to serious kidney problems like renal papillary necrosis , a condition where parts of the kidney die. NSAIDs can also lead to severe and sometimes fatal skin conditions such as: Erythroderma.

Is topical Voltaren safer than oral Voltaren?

The level of drug entering the bloodstream is much lower than when the NSAID is taken by mouth. For example, topical NSAIDs reduce the systemic exposure by almost 90 percent. This minimizes the risk of harmful side effects.

Why was Voltaren taken off the market?

A slew of studies, though, show diclofenac — sold under the brand names Voltaren, Cambia, Cataflam and Zipsor — is just as likely to cause a heart attack as the discredited painkiller Vioxx (rofecoxib), which was pulled from the U.S. market in 2004.

How many times a day can you use Voltaren gel?

For osteoarthritis of the knees, ankles, or feet using Voltaren® 1% gel: Adults—Apply 4 grams (g) to the affected skin areas four times a day (a total of 16 g each day). However, the total dose should not exceed 32 g per day over all affected joints. Use the enclosed dosing card to measure the appropriate dose.

How long is Voltaren gel in your system?

Diclofenac sodium (the medication in Voltaren gel) can stay in the body for nearly 3 weeks.

Does Voltaren gel affect blood pressure?

NSAIDs, including Voltaren Gel, can lead to high blood pressure or worsening of high blood pressure, which may add to the increased risk of heart attack and stroke. There is a potential for elevation in liver function tests during treatment with diclofenac containing products.

Is Voltaren gel safer than pills?

EVIDENCE-BASED ANSWER. Topical NSAIDs are associated with almost four times more local skin adverse events but about one-third fewer gastrointestinal adverse events than their oral counterparts in the treatment of chronic musculoskeletal pain up to 12 weeks.

What happens if you use too much diclofenac gel?

Diclofenac tablets and capsules can cause an ulcer in your stomach or gut if you take them for a long time or in big doses. There's also a small risk of heart failure or kidney failure if you take very big doses (150mg a day) for a long time. It's best to take the lowest dose that works for the shortest possible time.

When should you not use diclofenac gel?

Do not apply to skin that has any cuts, open wounds, infections or rashes. Apply the gel to the directed skin areas, using the dosing card to help apply the gel to the skin to up to 2 body areas. Do not apply to more than 2 body areas. Use your hands to gently rub the gel into the skin.

Can you use Voltaren if you have cirrhosis?

Recommendations. NSAIDs should be avoided in all patients with cirrhosis.

Does Voltaren affect kidneys or liver?

Get medical help right away if you have any very serious side effects, including: signs of kidney problems (such as change in the amount of urine, pink/bloody urine), unexplained stiff neck. Diclofenac may rarely cause serious (possibly fatal) liver disease.

What can replace Voltaren?

2) Pennsaid solution (diclofenac sodium 1.5%) is another topical treatment similar to Voltaren gel (also made by Endo) that is approved for the treatment of knee arthritis symptoms. The recommended dose is 40 drops per knee, four times a day.

Why can't you use Voltaren on your shoulder?

It's a potent medication that is very effective for many people and is often used for arthritis pain. For superficial joints – like hands, wrists and even knees – it can be very effective. However, the joints of the cervical spine in the neck, and most of the shoulder joint, are deeper than the Voltaren can penetrate.

Can you use Voltaren gel indefinitely?

Therefore, Voltaren can be used as an anti-inflammatory and analgesic agent not only in short-term therapy but also in the long-term treatment of chronic diseases.

What is the difference between Voltaren gel and diclofenac gel?

Voltaren Arthritis Pain vs. Diclofenac: What's the difference? With a proven safety profile for 10+ years, Voltaren Arthritis Pain Gel is an effective topical non-steroidal anti-inflammatory (NSAID) arthritis pain reliever. Diclofenac is the generic name for the active ingredient in Voltaren Arthritis Pain.

Does Voltaren Gel have heart risks?

This medicine may increase your risk of having a heart attack or stroke. This is more likely in people who already have heart disease or in people who use this medicine for a long time. This medicine may cause bleeding in your stomach or bowels.

What pain relief affects liver?

Acetaminophen or Tylenol® is the best known medication that can damage the liver. This medication is widely available without prescription and is present in many of the cold and flu remedies as well as in prescribed pain medications.

Which Voltaren is best for arthritis?

Voltaren gel, which is the form that is applied topically (to the skin), is most useful for osteoarthritis of the knees and hands.

Can I take Tylenol while using Voltaren gel?

Interactions between your drugs

No interactions were found between Tylenol and Voltaren.