What meds Cannot be taken with Synthroid?

The medicines and supplements that should not be taken within 4 hours of taking levothyroxine include:
  • Calcium supplements (including those found in multivitamins)
  • Iron supplements (including those found in multivitamins)
  • Antacids.
  • Sucralfate.
  • Phosphate binders (calcium carbonate, ferrous sulfate, sevelamer, lanthanum)


What medicines should not be taken with Synthroid?

A number of drugs have been shown to impair the absorption of levothyroxine; these drugs include calcium carbonate, aluminum- containing antacids, sucralfate, iron supplements, cholestyramine, sevelamer, and, possibly, ciprofloxacin, raloxifene, and orlistat.

What medications interfere with thyroid medication?

Specifically, antacids, calcium, cholesterol drugs, and iron supplements can each interfere with the way the thyroid hormone is absorbed. So, you should take these particular drugs four hours before or after taking your thyroid medication, according to the U.S. National Library of Medicine.


Does Synthroid interact with other medications?

There are 201 drugs known to interact with Synthroid (levothyroxine), along with 5 disease interactions, and 3 alcohol/food interactions. Of the total drug interactions, 179 are moderate, and 22 are minor.

How long after taking Synthroid can I take other medications?

Aim to take levothyroxine at least 2 hours before your other medications, or at least 4 hours after.


How to take Levothyroxine (Synthroid) Correctly | Side Effects All Patients Need to Know



Is it better to take Synthroid in the morning or at night?

There is consensus that levothyroxine should be taken in the morning on an empty stomach. A pilot study showed that levothyroxine intake at bedtime significantly decreased thyrotropin levels and increased free thyroxine and total triiodothyronine levels.

What are the rules for taking Synthroid?

Take levothyroxine once a day in the morning, ideally at least 30 minutes before having breakfast or a drink containing caffeine, like tea or coffee. Food and caffeinated drinks can both stop your body taking in levothyroxine properly so it does not work as well.

Why is it better to take Synthroid at night?

Conclusions: Levothyroxine taken at bedtime significantly improved thyroid hormone levels. Quality-of-life variables and plasma lipid levels showed no significant changes with bedtime vs morning intake. Clinicians should consider prescribing levothyroxine intake at bedtime.


Can you take Synthroid and vitamin D together?

Interactions between your drugs

No interactions were found between Synthroid and Vitamin D3.

Can I take Synthroid and blood pressure meds at same time?

Ideally, levothyroxine should be the only medication taken at bedtime. Just as with morning dosing, it is best to avoid co-administration with other medications such as statins, blood pressure drugs, and metformin.

What vitamins should you avoid with hypothyroidism?

According to the Mayo Clinic, supplements such as calcium, iron, multivitamins containing iron, and antacids containing magnesium or aluminum can potentially have interactions with thyroid medications.


How long after taking Synthroid can I drink coffee?

The researchers said the results are potentially good news for patients who have been instructed to take levothyroxine 30 to 60 minutes before coffee to avoid a drug interaction.

Is it OK to take Tylenol with Synthroid?

Interactions between your drugs

No interactions were found between Synthroid and Tylenol.

How far apart should you take Synthroid and vitamin D?

You took your thyroid medication with vitamin supplements

So space these at least 1 hour apart. Another supplement to watch out for is biotin. It's commonly taken for its hair, skin, and nail benefits. Biotin doesn't interfere with thyroid medication, but it can interfere with a thyroid blood test.


What is the difference between levothyroxine and Synthroid?

What's the difference between levothyroxine and Synthroid? Levothyroxine and Synthroid contain the same active (main) ingredient, levothyroxine, which is human-made T4. Levothyroxine is the generic name for Synthroid.

How many hours after taking Synthroid can I take vitamins?

Synthroid interactions with supplements

This may make Synthroid less effective than usual. Due to this risk, you should not take iron or calcium supplements at least 4 hours before or 4 hours after taking Synthroid. This should help prevent iron or calcium from affecting the level of Synthroid in your body.

What are long term side effects of Synthroid?

You may experience a racing heartbeat, chest pain, and tightness, or even a heart attack. Fast or irregular heartbeats (like atrial fibrillation), palpitations, and abnormal heart rhythms need to be treated appropriately. High levels of thyroid hormone can also lead to heart failure (Klein, 2007).


Does Synthroid make it hard to sleep?

At the correct dose, it is an effective treatment for many people. However, if someone is taking more than they need, they can experience side effects, including: inability to sleep.

What is the downside to taking levothyroxine?

Common side effects of levothyroxine include heat intolerance, a fast heart rate, and diarrhea. More serious levothyroxine side effects are also possible. If you experience side effects like tremors or mood changes, talk to your healthcare provider as soon as you can.

Do you have to drink full glass of water with Synthroid?

Take the tablets with a full glass of water as they may get stuck in your throat or cause choking or gagging. If you are giving levothyroxine to an infant, child, or adult who cannot swallow the tablet, crush and mix it in 1 to 2 teaspoons (5 to 10 mL) of water.


Why do you have to wait 30 minutes after taking Synthroid?

The absorption of levothyroxine in the gut is decreased when taking the hormone at the same time as calcium, iron and some foods and other drugs. Because of this, patients are usually instructed to take levothyroxine on an empty stomach 30-60 minutes before food intake to avoid erratic absorption of the hormone.

What is the new thyroid medication for 2022?

February 2022 sees two additional levothyroxine medicines introduced to the PBS: levothyroxine Eltroxin 125 micrograms (µg) tablet: new item listing.

What happens if you take thyroid medicine after eating?

Taking it with or too soon before or after a meal or snack could reduce absorption to 64%, from a high of 80% when you're fasting, according to the American Thyroid Association. ³ Just changing your timing could bring your thyroid levels back into a normal range.


Can Synthroid cause high blood pressure?

Heart problems

These side effects aren't common with Synthroid. Symptoms of heart problems from taking Synthroid can include: dizziness. high blood pressure.

Can I take Synthroid at 3am?

If you have an underactive thyroid gland, you need to take your medication every day at the same time. For most people, it doesn't really matter if you take your thyroid medicine in the morning or just before bed. The choice is really just a matter of what suits your lifestyle best.